Classes and Mode of Action of Antibiotics

Question 1

What antibiotics can work against BOTH gram-positive and gram-negative bacteria?

Answer 1

1. Sulfonamides
2. Cephalosporins
3. Quinolones

Question 2

What fungus was first found to produce Cephalosporins?

Answer 2

Cephalosporium acremonium

From a sewer in Sardinia (1948)

Question 3

Which antibiotic is known as a last resort antibiotic?

Answer 3

Vancomycin

Question 4

What TWO classes of antibiotics bind to the 30S subunit of the ribosome to inhibit protein synthesis?

Answer 4

1. Aminogycosides (Streptomycin)
2. Tetracyclines (Doxycycline)

Question 5

What classes of antibiotics bind to the 50S subunit of the ribosome to inhibit protein synthesis?

Answer 5

1. Linezolid
2. Chloramphenicol
3. Macrolides
4. Clindamycin
5. Streptogramins