Placental and Fetal Flashcards

1
Q

What happens during the first trimester to spiral arteries?

A

They become blocked. No maternal blood flowing so foetus rely on nutritional material in spaces between fetal tissue and maternal tissue.

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2
Q

What sort of placenta is found in humans?

A

Discoid placenta (placenta arranged in a circular shape).

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3
Q

Why do humans have a discoid placenta?

A

Increases in oxidative stress, increase in apoptosis and a decrease in proliferation result in placenta regressing.

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4
Q

When do the spinal arteries unplug?

A

During the second trimester.

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5
Q

Give 2 functions of the placenta.

A

Respiratory organ. Nutrient transfer. Excretion of fetal waste. Hormone synthesis.

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6
Q

What is the difference between the cytotrophoblast and the syncytiotrophoblast.

A

Cytotrophoblasts contain mononucleated cells. Syncytiotrophoblasts contain multinucleated cells.

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7
Q

What is the decida basalis?

A

Area of endometrium between the implanted chorionic vesicle and the myometrium, which becomes the maternal part of the placenta.

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8
Q

Empty spaces of the primary villi are known as…

A

Lacunae.

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9
Q

The syncytiotrophoblast penetrate what to develop the placenta.

A

Decida basalis

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10
Q

Define macrosomia.

A

Overweight at birth. Causes problems during labour, and increases the risk of a still birth.

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11
Q

How many arteries and veins are found within the umbilical cord?

A

2 arteries. 1 vein.

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12
Q

Are fetal arteries deoxygenated or oxygenated?

A

De-oxygenated.

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13
Q

Are fetal veins deoxygenated or oxygenated?

A

Oxygenated.

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14
Q

What are the three structures of the umbilical cord?

A

Body stalk. Vitelline duct. Allantois.

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15
Q

The endoderm develops the gut tube, which divides into 3 layers. What are these 3 layers?

A

Foregut. Mindgut. Hindgut.

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16
Q

What is the Vitelline duct? :

A

Open connection between the yolk sac, midgut at week 3.

17
Q

What is the Allantois?

A

Small hindgut outpocketing that grows into umbilical cord at week 3.

18
Q

Give 2 contents of the amniotic fluid.

A

Urine. Amniotic membrane secretions. Fetal lung secretions. Salivary secretions. Fetal epithelial cells.

19
Q

When do uterine spiral arteries do?

A

They play a vital role in supplying nutrients to the placenta and fetus from the second trimester.

20
Q

Give 2 adaptations of a fetal circulatory system.

A

Umbilical vein and artery. Ductus venosus. Foramen ovule. Ductus artiosus.

21
Q

Give 2 differences between pre and postnatal circulation.

A

Prescence of placental circulation. Lack of circulation to lungs.

22
Q

What is a ductus venosus?

A

It shunts a portion of the left umbilical vein blood flow directly to the inferior vena cava. Thus, it allows oxygenated blood from the placenta to bypass the liver.

23
Q

What is a foramen ovale?

A

Hole between right and left atria. Allows blood to bypasss pulmonary circulation.

24
Q

What is a ductus arteriosus?

A

Shunt connecting the pulmonary artery to the aorta, therefore blood can ignore the lungs (inactive).

25
Q

Name 1 of the 3 changes at delivery.

A

Closure of the foramen ovale, ductus arteriosus and ductus venosus.