Placenta path I Flashcards
what is difference of fetal and maternal surface of placenta
fetal surface is flat
maternal has cotyledons
what is important about looking at placenta post delivery
look at the cotyledons of the maternal size to make sure there isnt anything missing that could still be in mother attached to uterus
what is important about looking at umbilical cord after birth
see how many aa/vv because if 2, 35% assoc with structural and chromosomal abnormalities
when does placental implantation take place after fertilization
1-2 weeks
what are the early functions needed for placental implantation
produce hCG to prevent loss of corpus luteum
re-model spiral aa for nutrition
anchoring villi
absorptive villi
what occurs to endometrium under unfluence of P after ovulation
becomes secretory and blood vessel rich in preparation for implantation of the blastocyst
where does exchange of fetal maternal blood take place
in the intervillous spacec between the choirionc villi surrounded by cytotrophoblasts and syncytiotrophoblasts
what happens to smooth muscle cells of the apiral aa in pregnancy
invaded by endovascular cytotophoblasts which create high P arteriole system and low R lacunar system for the blood to pool and exchange nutrients
abnormalities of the cytotrophoblasts can lead to what condition
preeclampsia
metabolic transfer between mom and fetus occurs through what cells
syncytiotrophoblasts
spontaneous abortions occur when
<12 weeks
risk factors for spont abortions
smoking
inc maternal age
previous spont abortion
what fetal factors could lead to spont abortion
chromosomal abnormalities
hydatidiform mole
neural tube defects
what maternal factors could lead to spont abortion
endocrine disorders luteal phase defect physica uterine abnormalities systemic disorders TORCH infections blood type incompatibility
What are the TORCH pathogens
toxo, other, rubella, CMV, HSV
spont abortion in 1st trimester is usually due to what
chromosomal abnormality