Placenta path I Flashcards

1
Q

what is difference of fetal and maternal surface of placenta

A

fetal surface is flat

maternal has cotyledons

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2
Q

what is important about looking at placenta post delivery

A

look at the cotyledons of the maternal size to make sure there isnt anything missing that could still be in mother attached to uterus

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3
Q

what is important about looking at umbilical cord after birth

A

see how many aa/vv because if 2, 35% assoc with structural and chromosomal abnormalities

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4
Q

when does placental implantation take place after fertilization

A

1-2 weeks

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5
Q

what are the early functions needed for placental implantation

A

produce hCG to prevent loss of corpus luteum
re-model spiral aa for nutrition
anchoring villi
absorptive villi

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6
Q

what occurs to endometrium under unfluence of P after ovulation

A

becomes secretory and blood vessel rich in preparation for implantation of the blastocyst

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7
Q

where does exchange of fetal maternal blood take place

A

in the intervillous spacec between the choirionc villi surrounded by cytotrophoblasts and syncytiotrophoblasts

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8
Q

what happens to smooth muscle cells of the apiral aa in pregnancy

A

invaded by endovascular cytotophoblasts which create high P arteriole system and low R lacunar system for the blood to pool and exchange nutrients

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9
Q

abnormalities of the cytotrophoblasts can lead to what condition

A

preeclampsia

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10
Q

metabolic transfer between mom and fetus occurs through what cells

A

syncytiotrophoblasts

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11
Q

spontaneous abortions occur when

A

<12 weeks

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12
Q

risk factors for spont abortions

A

smoking
inc maternal age
previous spont abortion

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13
Q

what fetal factors could lead to spont abortion

A

chromosomal abnormalities
hydatidiform mole
neural tube defects

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14
Q

what maternal factors could lead to spont abortion

A
endocrine disorders
luteal phase defect
physica uterine abnormalities
systemic disorders
TORCH infections
blood type incompatibility
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15
Q

What are the TORCH pathogens

A

toxo, other, rubella, CMV, HSV

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16
Q

spont abortion in 1st trimester is usually due to what

A

chromosomal abnormality

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17
Q

spont abortion in 2nd trimester is usually due to what

A

mechanical

18
Q

spont abortion in 3rd trimester is usually due to

A

fetoplacental unit

19
Q

can you have bleeding during pregnancy that is okay

A

yes! painless usually

20
Q

predisposing conditions to ectopic pregnancies

A

PID, appendicitis, endometriosis, previous surgery, IUDs

21
Q

clinical Sx of ectopic pregnancies

A

severe abdominal pain: hematosalpinx

tubal rupture: intra-abdominal hemorrhage, shock

22
Q

Dx ectopic pregnancy

A

beta hCG, US, laparoscopy

23
Q

what is dichorionic diamnionic pregnancy

A

fraternal twins, each has on amnion, own chorion

24
Q

what is dichorionic diamnionic fused pregnancy

A

fraternal that share septum of chorion

25
Q

what is monochorionic diamnionic amnion

A

share chorion, separate amnion

26
Q

what is monochorionic monoamnionic

A

share everything– identical

27
Q

if jelly roll of placenta shows amnion on either side of thick chorion know its what type pregnancy

A

di di, fraternal twins

28
Q

if there is one chorion and 2 amnion on jelly roll of placenta

A

monozygous, identical twins

29
Q

what condition of twins can lead to death of one or both fetuses

A

monochorionic because can have disproportionate sharing of fetal circulations

30
Q

What is placenta previa

A

implantation in lower uterine segment

31
Q

abruptio placenta

A

retroplacental hemorrhage

32
Q

placenta accreta

A

placenta infiltrates in myometrium from lack of intervening decidua
placenta cannot detach after delivery

33
Q

what is the most common cause of antepartum hemorrhage

A

placenta previa

34
Q

how do we prevent antepartum hemorrhage in placenta previa

A

C section

35
Q

Sx placenta previa

A

painless bleeding in 3rd trimester

36
Q

Sx abruptio placenta

A

painful bleeding

37
Q

significant complication of abruptio placenta

A

preeclampsia

38
Q

bleeding from abruptio placenta requires what Tx

A

immediate delivery

39
Q

loss of decidua basalis because placenta attached to myometrium is called what

A

placenta accreta

40
Q

complication of placenta accreta

A

uterine rupture

41
Q

what are the types of placenta accreta

A

accreta is most shallow
increta
percreta- deep

42
Q

predisposing conditions for placenta acreta

A

endometrial scarring
previous C section
endometrial inflammation