Ovaries path II Flashcards
Sx for surface epithelial tumors
lower abdominal pain, GI complaints, ascites GU complaints, pelvic pressure, progressive weakness, weight loss, cachexia end stage
what is peritoneal carcinomatosis
diffuse seeding of peritoneum
Tx for surface epithelial tumors
surgery
where do surface epithelial tumors mets to
mesothelial surface (ovarian serous carcinoma to malignant ascites
lymph nodes
liver, lungs, bone, CNS
which serum to ascites albumin gradient is characteristic of peritoneal carcinomatosis
<1.1 g/dL
low albumin gradient
most common cancer to cause ascites
ovary- serous type
what are the hormonaly active tumors that secrete E in postmenopausal women
granulosa theca cell tumors
what biomarker is used to Dx granulosa theca cell tumor
inhibin
FoxL2 mutation
Call Exner bodies on histo
granulosa theca cell tumor
what are fibromas
solid white hard fibrous tumor
usually unilateral
what syndrome are fibromas assoc with
meig syndrome: ascites pleural effusion and ovarian fibroma that resolves with resection of fibroma
which tumors can produce androgens
sertoli leydig cell tumors
leads to virilization, hirsutism, male escuthecon, deepen voice, increase clitoris size, defeminization
germ cell tumors are dangerous in what age group
children- malignant
adults- benign
what classifies a benign cystic teratoma or dermoid “mature teratoma”
2 or 3 germ cell lines
rokitanski nodule on cysts wall
what type of cancer can develop(rare) from benign teratoma
SCC
