Pig CV and Respiratory Disease Flashcards
Which antibodies are produced in the airway and alveoli?
- airway IgA
- alvioli IgG
How may defence mechanisms be damaged?
- damage to nasal turbinates
- damage to mucociliary escalotir
- viral damage of macrophages
- hypoxia induced reduction of macrophage oxidative phosphorylation
Which pathogen can exacerbate all other respiratory diseases of the pig?
PCV2
- immunosuppressive
- endemic on 90% farms
What age are majority of diseases seen in pigs?
- post-weaning
> weaning stressful! - change of feed, pens, mixing, no mother, medical tx
- early weaning? can help minimise spread mother - young, can ^ susceptibility
Which pathogens/diseases cauuse NEONATAL respiratory disease?
- actinobacillus suis
- bordatella bronchisepticum
- progressive atrophic rhinitis
Which pathogens/diseases affect pre-weaned pigs?
- progressive atrophic rhintiis (bordatella bronchiseptica)
- inclusion body rhinitis (pig CMV)
- enzootic pneumonia (Mycoplasma sp.)
- PRRSV (repro and resp syndrome)
- Glassers disease (Haemophilus parasuis)
Which pathogens/diseases occour in weaner, growers and finishers?
- bordatella bronchiseptica
- glassers disease
- actinobacillus pleuropneumonia
- pasturella multiocida
- mycoplasma hyopneumonia (EP)/hyorrhinis
- PRRSV
- PRCV (porcine resp coronavirus)
- influenza
- PMWS?/PCVAD
- aujesky’s disease (pig herpesvirus 1)
Which pathogens cause significant respiratory disease in non-immune adult pigs?
- Glassers disease (actinobacillus pleuropneumoniae)
- Pasteuruellosis
- Enzootic pneumonia
- PRRSV
- Influenza
What is the most common pig pathogen according to AHVLA case reports?
Pasteurella multocida
but most common will not have been reported to AHVLA!
Is mycoplasma hyopneumoniaueof economic importance? What disease does it cause?
YES!
- 30-80% pigs have lesions at slaughter
= enzootic pneumonia
How do mycoplasmas cause disease?
- damage mucociliary escalator -> 2* infections
- cause disease themselves
Clinical signs and diagnosis of m. hyopneumomniae?
- weaned pigs
- coughing
- v FCE
- variance in growth rates
- 2* infections
> dx - clinical signs
- lung lesions at slaughter
- culture/PCR
- histology
- serology
Which pathogen has 12 subtypes? What type of disease does this cause?
- actinobacilus pleuropneumoniae
- > explosive outbreaks pneumonia, ^ morbidity and mortality OR seroconversion with few clinical signs
Dx of APP? (actinobacillus pleuropneumoniae)
> clinical signs - acute fatal respiratory disease - fibrinous pleuritis - firm lung infarcts (lesions largely produced by the toxins) > diagnosis - culture - PCR - lung lesions - serology
Epidemiology of APP?
- fighting after mixing (direct contact)
- aerosol limited
- survives in water/mucus
- ifferent serotypes in different countries
