Physiology of Satiety and Feeding Flashcards
How is energy usually stored
As fat
How do you calculate BMI
Weight (kg) / Height (m)^2
What are the BMI ranges
Up to 25 = thin/ healthy
25 - 29.9 = overweight
30 - 39.9 = obese
>40 = morbidly obese
What factors are responsible for obesity
Genetics + Enviroment
Name a survival adaptation
Adipose tissue
Health concerns as a result of obesity
Stroke (hypertension) Diabetes Gout Cancer - prostate, breasts, uterus and colon NAFLD Heart disease Gallbladder disease Respiratory disease- sleep apnoea
Ventromedial hypothalamus is responsible for
obesity
lateral hypothalamus is responsible for
leanness
define adiposity
state of being obese
satiation
feeling of fullness during a meal
satiety
period of time between termination of one meal and initiation of next
explain cholecystokinin
released from enteroendocrine cells in the duodenum and jejunum
released in proportion to lipids and proteins during a meal
what hormones are released in response to eating
leptin from fat cells
insulin from pancreatic beta cells
Explain the role of ghrelin
Released from oxyntic cells
During hypoglycaemia and fasting
Peripheral ghrelin –> decreases energy expenditure, decreases fat utilization, stimulates food intake
what two satiation signals are released from oxyntic cells
peptide YY
Glucagon like peptide 1