physiology of aging

Question 1

lots of ROS in what organelle

Answer 1

mitochondria

Question 2

superoxide dismutase helps w what ROS

Answer 2

superoxide anion radical

Question 3

catalase helps w what ROS

Answer 3

hydrogen peroxide

Question 4

glutathione peroxidase helps w what ROS

Answer 4

hydrogen peroxide and reduced glutathione

Question 5

glycation is what

Answer 5

the nonenzymatic reactions between the carbonyl groups of reducing sugars and the amino groups of macromolecules to form advanced glycation end products (AGEs)

Question 6

proteins containing AGE can be affected how

Answer 6

structure, function, DNA all can be affected

Question 7

damage to what organelle can lead to aging

Answer 7

mitochondrial damage bc less production of ATP = loss of cell function

Question 8

what are two common ROS

Answer 8

hydrogen peroxide
hydroxyl radical
superoxide anion radical
nitric oxide

Question 9

what is lipofuscin

Answer 9

products that should be degraded by lysosomes that are still around

Question 10

as you get older, what happens to ur telomeres

Answer 10

gets shorter (limitations in cell division)

Question 11

what type of fat increases w adult age and where

Answer 11

adipose fat
abdominal viscera and in abdominal subcuntaneous tissue

Question 12

sarcopenia

Answer 12

steady loss in skeletal muscle mass

Question 13

bone loss leads to

Answer 13

osteoporosis

Question 14

food restriction extends life by decreasing

Answer 14

oxidative stress