Physiology (Autonomic Nervous System) Flashcards
Q: What is the general function of the sympathetic nervous system?
Catabolic and energy-consuming system (stress, fight, fear, and flight).
Q: What are the sympathetic effects on the eye?
Dilator pupillae muscle: Contraction → Mydriasis (pupil dilatation).
Smooth muscle of upper eyelid: Contraction → widening of palpebral fissure → increased field of vision.
Ciliary muscle: Relaxation → decreased lens power → far vision.
Müller’s muscle (animals): Contraction → eyeball protrusion → exophthalmos.
Conjunctival vessels: Vasoconstriction (VC).
Q: What are the sympathetic effects on the skin?
Sweat glands: Stimulates secretion.
Cutaneous blood vessels: Vasoconstriction.
Piloerector muscles: Contraction → hair erection
Q: What are the sympathetic effects on salivary glands?
Trophic secretion of saliva: Small amount, concentrated, and viscid
Q: What are the sympathetic effects on the brain and cerebral circulation?
Cerebral circulation: Increased blood flow (due to increased ABP) with mild vasoconstriction.
Brain: Increased mental alertness
Q: What are the sympathetic effects on the heart?
ncreases all cardiac properties:
Rate and force of contraction.
Excitability.
Rate of conduction.
Coronary blood vessels: Indirect vasodilatation.
Q: What are the sympathetic effects on the lungs?
Bronchodilatation.
Mild vasoconstriction of pulmonary blood vessels.
Q: What causes Horner’s Syndrome, and what are its manifestations?
Cause: Lesion on one side of the cervical sympathetic chain.
Manifestations (on the same side):
Miosis: Constricted pupil.
Ptosis: Drooping of the upper eyelid.
Anhidrosis: Absence of sweating.
Warm and red skin: Due to vasodilatation
Q: What is the origin and relay of the sympathetic fibers for head, neck, and thoracic viscera?
Head & Neck:
Origin: Lateral horn cells of T1-T2.
Relay: Cervical ganglia.
Thoracic Viscera:
Origin: Lateral horn cells of T1-T4.
Relay: Cervical and upper thoracic ganglia.
Q: What is the origin and relay of sympathetic fibers to the abdominal viscera?
Origin: LHCs of T5-T12.
Relay: Greater splanchnic nerve → coeliac & superior mesenteric ganglia.
Q: What are the sympathetic effects on the gastrointestinal tract?
Relaxation of smooth muscles (stomach, small intestine, proximal large intestine).
Contraction of sphincters (e.g., pyloric sphincter).
Q: What are the sympathetic effects on abdominal blood vessels?
Vasoconstriction of arterioles supplying abdominal viscera.
Vasodilatation in specific arterioles.
Q: What are the sympathetic effects on the liver, spleen, and adrenal medulla?
Liver: Stimulates glycogenolysis → increases blood glucose.
Spleen: Contraction of capsule → releases stored blood (RBCs).
Adrenal Medulla: Secretes adrenaline and noradrenaline into blood
Q: What is the origin and relay of sympathetic fibers to the pelvic viscera?
Origin: LHCs of T12-L2.
Relay: Lesser splanchnic nerve → inferior mesenteric ganglion.
Course: Postganglionic fibers run with blood vessels to pelvic organs
Q: What are the sympathetic effects on the gastrointestinal tract in the pelvis?
Relaxation of smooth muscles (distal large intestine & rectum).
Contraction of internal anal sphincter → fecal retention
Q: What are the sympathetic effects on the urinary bladder?
Relaxation of bladder wall.
Contraction of internal urethral sphincter → urine retention.
Q: What is the function of the sympathetic system on the adrenal medulla?
Stimulates secretion of adrenaline and noradrenaline directly into the bloodstream → enhances “fight or flight” response.
Q: What are the sympathetic effects on the spleen?
Contraction of the splenic capsule → releases stored blood (RBCs) into circulation.
Q: How does the sympathetic system affect gastrointestinal sphincters?
Causes contraction of sphincters (e.g., pyloric sphincter, internal anal sphincter) → retention of contents (food or feces).
Q: What is the sympathetic effect on blood glucose levels?
Stimulates glycogenolysis in the liver → increases blood glucose to provide energy for “fight or flight” situations.
Q: What happens to the urinary bladder under sympathetic control?
Relaxation of bladder wall muscles → prevents urination.
Contraction of the internal urethral sphincter → retains urine.
Q: How does the sympathetic system regulate blood vessels?
Vasoconstriction of arterioles in abdominal and pelvic viscera → redirects blood to vital organs (brain, heart, muscles).
Selective vasodilatation of certain arterioles when necessary.
Q: Summarize the sympathetic effects on abdominal GIT.
Abdominal GIT:
Relaxes smooth muscles (stomach, small intestine, proximal large intestine).
Contracts sphincters (pyloric sphincter).