cartilage hitso Flashcards
What is Cartilage?
Cartilage = Chondro
📌 Definition: A type of connective tissue (CT) with a firm, rubbery, and flexible matrix.
Characteristics of cartilage
✅ No nerves
✅ Avascular (no blood vessels)
✅ Nutrition via diffusion from surrounding tissues or synovial fluid
Functions of Cartilage
✅ Reduces friction at joints
✅ Acts as a shock absorber (resists mechanical compression)
✅ Provides shape, support, and
flexibility to body structures
✅ Keeps airways patent
✅ Important for bone development & growth
Structure of Cartilage
3 Main Components:
1️⃣ Cells → Chondroblasts & Chondrocytes
2️⃣ Matrix → Firm, rubbery, flexible
3️⃣ Fibers → Collagen (Type I & II) & Elastic fibers
4️⃣ Perichondrium (except at articular surfaces)
Perichondrium
Definition: A dense fibrous connective tissue surrounding cartilage (except at joints).
📌 Structure:
Outer fibrous layer: Fibroblasts, Collagen Type I, Blood vessels
Inner cellular layer: Chondroblasts
functions of Perichondrium
Functions:
✅ Provides nutrition (blood vessels)
✅ Attachment site for muscles
✅ Supports appositional growth
Cartilage Cells???
1️⃣ Chondroblasts (Immature - Builder Cells)
📍 Origin: From mesenchymal cells
📍 Site: Inner perichondrium
📍 Shape: Flat to oval
📍 Function:
Produces fibers & matrix
Converts into chondrocytes
Responsible for appositional growth (surface growth)
———————————-
Chondrocytes (Mature - Maintaining Cells)
📍 Origin: From chondroblasts
📍 Site: Inside the cartilage (in lacunae)
📍 Shape:
Oval (superficial layers)
Rounded (deep layers)
📍 Function:
Maintains matrix
Responsible for interstitial growth (growth from inside)
types of Cartilage Growth????
📌 1. Appositional Growth
✅ Growth from the outside
✅ Occurs when chondroblasts differentiate into chondrocytes
📌 2. Interstitial Growth
✅ Growth from inside
✅ Chondrocytes divide and produce new matrix
Types of Cartilage
📌 Cartilage Types (Based on Fiber Type):
1️⃣ Hyaline Cartilage (Type II Collagen)
2️⃣ Elastic Cartilage (Elastic fibers)
3️⃣ Fibrocartilage (Type I Collagen)
Characteristics of Hyaline Cartilage
✅ Most common type
✅ Smooth & glassy appearance
✅ Type II Collagen (not visible in LM)
Functions of Hyaline Cartilage
✅ Provides frictionless surface for joints
✅ Supports respiratory passages
✅ Forms fetal skeleton
✅ Aims in bone growth (epiphyseal plate)
Sites of Hyaline Cartilage
✅ Articular cartilage (joints)
✅ Costal cartilage (ribs)
✅ Epiphyseal plates
✅ Respiratory passages (trachea, bronchi)
Characteristics of Elastic Cartilage
✅ Contains abundant elastic fibers
✅ Yellow color, very flexible
✅ Recovers shape after deformation
Functions of Elastic Cartilage
✅ Supports movable body parts
✅ Maintains shape & flexibility
Sites of Elastic Cartilage
✅ Ear pinna
✅ External auditory canal
✅ Eustachian tube
✅ Epiglottis
Characteristics of Fibrocartilage (White Cartilage)
✅ Strongest & least flexible type
✅ Scanty matrix
✅ NO Perichondrium
✅ Contains Type I Collagen (thick bundles)
Functions of Fibrocartilage (White Cartilage)
✅ Provides strength
✅ Shock absorption in high-pressure areas
Sites of Fibrocartilage (White Cartilage)
✅ Mandibular Joint
✅ Intervertebral Discs
✅ Symphysis Pubis
✅ Sternoclavicular Joint
Structure of Intervertebral Disc
📌 Composed of Two Parts:
1️⃣ Outer Fibrous Ring (Annulus Fibrosus) → White fibrocartilage (Type I Collagen)
2️⃣ Inner Soft Core (Nucleus Pulposus) → Jelly-like mass (Type II Collagen)