bone histo Flashcards
What is Bone Tissue?
π‘ Bone = Osteo
π A calcified connective tissue with calcium and phosphate salts.
What are the Two Bone Coverings?
π Periosteum (outer) & Endosteum (inner).
What are the Two Layers of the Periosteum?
π Outer fibrous layer β Collagen, fibroblasts, blood vessels.
π Inner cellular layer β Osteogenic cells, osteoblasts.
What are the Four Bone Cells?
π Osteogenic cells β Stem cells.
π Osteoblasts β Bone-forming cells.
π Osteocytes β Mature bone-maintaining cells.
π Osteoclasts β Bone-resorbing (eating) cells.
What is the Function of Osteogenic Cells?
π Bone stem cells that divide & form osteoblasts.
What is the Function of Osteoblasts?
π Produce bone matrix (osteoid) & initiate calcification.
What is the Function of Osteocytes?
Maintain bone matrix & exchange nutrients via canaliculi.
What is the Function of Osteoclasts?
π Break down bone using enzymes & acid (bone resorption).
What Type of Collagen is in Bone?
π Type I Collagen (acidophilic matrix).
What are the Two Types of Bone Growth?
π Appositional growth β Increases width by osteoblast activity .
π Interstitial growth β β Does NOT occur in bone.
What is the Function of the Endosteum?
π Bone growth & repair (contains osteogenic cells & osteoblasts).
What is an Osteoid?
π Uncalcified, immature bone matrix.
What is Howshipβs Lacuna?
π Bone erosion pit where osteoclasts break down bone.
How Do Osteocytes Communicate?
π Via gap junctions in canaliculi.
What is the Main Function of Bone Tissue?
π Support, protection, movement, mineral storage, blood cell production
What is Found in the Haversian Canal?
π Blood vessels & nerves.
What Connects Haversian Canals?
π Volkmannβs Canals.