Physiology Flashcards
pacemaker potential is due to
decrease in K+ efflux
Depolarization due to
activation of L-type calcium channels, causing calcium influx
repolarisation due to
activation of K+ channels resulting in potassium efflux
phase 0- pacemaker
depolarisation
ca channels open, Na channels close
slow conduction= AV nodal delay
phase 3- pacemaker
repolarisation
Ca channels close, K+ channels open= K efflux
phase 4- pacemaker
Slow depolarisation funny current that has mixed Na/K inward current causing slow depolarisation important to determine HR adenosine > decrease catecholamines > increase
phase 0- ventricular muscle
depolarisation due to Na influx
phase 1- ventricular muscle
closure of Na channels and transient K efflux
phase 2- ventricular muscle
plateau phase
Ca2+ influx through L type Ca2+
phase 3- ventricular muscle
closure of Ca channels and K efflux
phase 4
resting potential due to K efflux