geeky

Question 1

Jejunal biopsy findings showing deposition of PAS-positive macrophages in the lamina propria

Answer 1

whipples disease

Question 2

Transmural inflammation and non-caseating granulomas

Answer 2

Crohn’s disease

Question 3

subtotal villous atrophy, increased intraepithelial lymphocytes, and crypt hyperplasia on duodenal biopsy

Answer 3

coeliac disease

Question 4

most common complication 24 hours post MI

Answer 4

arrhythmia

Question 5

most common composition of gallstones

Answer 5

cholesterol, bilirubin, bile salts

Question 6

gold standard imaging for suspected pulmonary fibrosis

Answer 6

HRCT

Question 7

air crescent sign

Answer 7

aspergillosis

Question 8

cholangiocarcinoma

Answer 8

biliary tree cancer

Question 9

hypertension in arms but hypotension in legs

Answer 9

coarction of the aorta

Question 10

persistent hemorrhoidal disease management

Answer 10

banding of hemorrhoids
inject the haemorrhoid with sclerosant agents (doxycycline)
colonoscopy or sigmoidoscopy in young patients

Question 11

main peri-MI cause of death

Answer 11

ventricular arrhythmia

Question 12

positive test for perinuclear anti-neutrophil cytoplasmic antibodies

Answer 12

PSC

Question 13

elevated ALP and bilirubin

Answer 13

stone in common bile ducts

Question 14

indicates diagnosis of acute cholecytitis

Answer 14

gallbladder thickness >3mm

sometimes raised ALP bilirubin mostly normal

Question 15

first line treatment of ascites secondary to liver cirrhosis

Answer 15

spironolactone

Question 16

bat wings on cxr

Answer 16

patchy peripheral shadowing

alveolar oedema

Question 17

solitary well defined painful lesion in the mouth

Answer 17

apthous ulcer

Question 18

management of apthous ulcer

Answer 18

topical steroids and topical lidocaine for pain

Question 19

diagnosis of TB

Answer 19

send of 3 sputum cultures

Question 20

test to check if patient has been exposed to tb

Answer 20

tuberculin skin test

Question 21

paraneoplastic features of squamous cell carcinoma

Answer 21

parathyroid hormone-related protein (PTH-rp) secretion causing hypercalcaemia
clubbing
hypertrophic pulmonary osteoarthropathy (HPOA)
hyperthyroidism due to ectopic TSH

Question 22

paraneoplastic features of SCLC

Answer 22

ADH
ACTH - not typical, hypertension, hyperglycaemia, hypokalaemia, alkalosis and muscle weakness are more common than buffalo hump etc
Lambert-Eaton syndrome

Question 23

‘Red-currant jelly’ sputum

Answer 23

Klebsiella pneumoniae

Question 24

CXR of aortic dissection

Answer 24

widened mediastinum

Question 25

pathology of appendicitis

Answer 25

obstruction by faecolith- leads to a closed system and build of appendiceal mucocele or thrombosis of appendicular artery

Question 26

what enzyme does warfarin inhibit

Answer 26

epoxide reductase preventing Vitamin K from being converted to its activated form

Question 27

MoA of Ranitidine

Answer 27

competitive antagonist of the H2 receptors on gastric parietal cells

Question 28

most common site of intussusception

Answer 28

ileocolic

Question 29

organism causing rheumatic fever

Answer 29

group A beta-haemolytic strep

Question 30

treatment of rheumatic fever

Answer 30

penicillin

Question 31

first heart sound

Answer 31

closure of mitral and tricuspid

Question 32

pulse in aortic stenosis

Answer 32

slow rising

Question 33

Conn's syndrome

Answer 33

health problem that occurs when the adrenal glands make too much aldosterone causes hypertension

Question 34

third heart sound is a sign off

Answer 34

HF

Question 35

JVP in constricted pericarditis

Answer 35

raised

Question 36

ankle pressure in critical limb ischaemia

Answer 36

<50

Question 37

JVP in AFib

Answer 37

absent a waves

Question 38

Where are the arterial baroreceptors located?

Answer 38

carotid sinus and aortic arch

Question 39

what nerve innervates the pericardium

Answer 39

phrenic nerve

Question 40

Clopidogrel MoA

Answer 40

DP receptor antagonist thus inhibiting platelet activation and clot formation

Question 41

blood marker for acute liver failure

Answer 41

PTT

Question 42

Histology of coeliac disease

Answer 42

villous atrophy, raised intra-epithelial lymphocytes, and crypt hyperplasia

Question 43

ST segment elevation in V1 and V2 leads, followed by a negative T wave associated with syncope

Answer 43

Brugada syndrome