Physiology Flashcards
Resting Membrane Potential
-70 to -90 mV
Depolarization
-70 to +30 mV
Threshold = -55 mV (
Na+ influx
Re-polarization
+30 to -75 mV
Efflux of K+ ions
Hyperpolorization
-75 to -90 mV
K+ leakage
All or non law
Applied to AP
P wave
Atrial depolarization (contracts)
QRS wave
Atrial re-polarization (relaxes) Ventricular depolarization (contracts)
T wave
Ventricular re-polarization (relaxes)
SA node
60 -90 bpms
AV node
30-50 bpms
Controls PQ interval
His bundle and Purkunje Fibers
10-20 bpms
Controls QRS unit
Low ST interval
Myocardial Infarction
Adenohypophysis
TSH ACTH GTH FSH LH Prolactin (NB for diagnosis of pathology in pituitary gland) GH Melanocyte SH
Neurohypophysis
Vasopressin/ADH (Increases tubular H2O absorption and controls bp)
Oxytocin (stimulates milk production and uterus contraction)
Hyperthyriodism
Graves disease
Hypothyriodism
Hashimotos disease
Calcitonin
Cells that produce calcitonin can be stained by silver
Produced by thyroid
Bone mineralization
Pararthyriod hormone
Bone demineralization
Produced by thyroid
Conns Disease
Increased levels of aldosterone
Cushings syndrome
Increased cortisol due to genetic factors
Cushings disease
Increased cortisol due to pituitary adenoma or trauma to the pituitary
Brainstem - Midbrain
Red nucleus (Injury causes flexed muscles) - Tension of flexor muscles
Brainstem - Pons
Quadrigeminal Plate
- Post/Sup = Pupil reflex
- Inf/Ant = Orientation and balance / tension of extensor muscles
Brainstem - MO
Respiratory center
Deglutition (swallowing) center
Brainstem - Cerebellum
Coordination of movement and speech
Spinal cord
Anterior = Motor Posterior = Sensory
SNS vs PNS
SNS = uses adrenaline PNS = uses acetycholine
IgA
Provides immunity in the oral cavity
IgE
Allergic reaction
IgM
Primary/acute infections
IgG
Secondary/chronic infections
G cells
Produce gastrin
Parietal cells
Produce HCL
Chief cells
Poduce pepsin ( digests proteins)
Bleeding
`Decreases haematocrit rate)
Vagus n
Stimulates PaNS Decreases HR (decreased contraction rate)
Superficial vs Deep haemorrhage
Sup = Platelet dysfunction (e.g. Punctata) Deep = Coagulation factors dysfunction
Waved/ Partial tetanus
Muscle contraction during relaxation
Holotetanus
Muscle contraction during movement
Min BV through lungs
Equal to Min BV through heart
Isometric contraction
Static period where heart valves are closed
Lens
Responsible for refracting power of eye
Renin and Erythropoietin
BP regulation
Glomerulus
Filters cells and proteins in blood
Tubules
Reabs electrolytes, glucose and H2O
Excretes urea
Glomerulonephritis
Inflammation of filter
Affects filtration
Pyelonephritis
Inflammation of tubule
Heart chamber pressures
RA = 0-10 mmHg LA = 0-20 mmHg RV = 0-60 mmHg LV = 0-120 mmHg
Functional Residual Capacity
Vol that stays in the lungs after expiration
Cardiomyocytes from V/A
Cant generate impulses automatically
Vestibular receptors
Responsible for balance
Super distended heart (extension)
Causes secretion of natruretic hormone
Kidney secretions
Exocrine = Erythropoietin (stimulaed by hypoxia) Endocrine = Renin
Spinothalamic tract
Responsible for pain and temperature
Increased oncotic pressure (E.g. Increased albumin)
H2O moves from int. fluid to capillaries
Anephric
Missing a kidney
Anemia due to decreased erythropoietin
Bile acids
Emulsify fats for digestion
Thyroxin
Thermoregulatory hormone
Aldosterone
Allows for min loss of Na+ in sweat
Post vs Pre Central Gyrus
Post = Sensory Pre = Motor
Increased glucose in blood
H2O moves from cell to IF
Middle frequency sounds
Middle part of helix/cochlear
Cattarhal inflammation
Inflammation of mucus membranes (E.g. rhinitis etc)
ESR
ESR increases when albumin decreases
Increases during starvation
Protein levels
<62 = Increased oncotic pressure (Increased filtration and decreased re-absorption)
Pancreatic Juice
Contains tripsin, lipase and amylase
Cholecystokinin stimulates pancreatic juice secretion
Injury to SCM
Affects inpiratory reserve volume
Pavlov classification
Phlegmatic = Balanced nervous activity Sanguine = High working activity
Acetycholine
Neurotransmitter found in sympathetic neurosynapses
Damage to reticular formation system
Prolonged deep sleep
Proprioreceptors
Muscle spindles = measure tension
Golgi tendon = measure length
Packed Cell Vol
Decreases when you loose blood
Bronchospasms
Block M cholinoreceptors to decrease
Diver reflex
Triggers refectory apnea
Moving from horizontal to vertical
Reflectory vasoconstriction of lower limb veins
Surfactant deficiency
Pulmonary collapse
Receptors of Ach
In neuromusucular synapse
Isometric vs Isotonic
Isometric = holding a load (muscle stays the same, tension increases) Isotonic = Waving your arm (muscle length changes, tension remains the same)
Diffusing lung capacity
Decreases with increased alveolar membrane thickness
Damage to C1- C4 and below C4
C1-C4 = Death (no respiration) C4 = Maintain respiration
Vagus damage
Deep and infrequent breathing
How to decrease gastric juice secretion
Block histamine receptors
Alpha 1,2 and Beta 1,2 receptors
Alpha 1 = smooth mm
Alpha 2 = adrenal gland
Beta 1 = heart
Beta 2 = bronchi (lungs)
Dry heat sterilization
Sterilizes pipettes etc
Depression of R-R interval
Heart hurry
Delayed AV node conduction
Prolonged P-Q interval
Aldosterone
Increases K+ and Na+ excretion
Reciprocal movement
One muscle contracts while the other relaxes
Cholagogues
Billiary excretion and intestinal motility
Catecholamines
Increase BP