Pharmacology Flashcards
Aspirin
Prevents thrombosis
Inhibits Cox 1 in platelets (prevents aggregation)
Celecoxib
Selective NSAID given for arthritis if patient has peptic ulcer history
Lidocaine
Local anesthetic given via IV for ventricular paroxysmal arrhythmia
Parkinsons
In Krok = Increased dopamine levels (should be decreased)
Levodopa = synthetic version of dopamine
Atropine SE
Dry mouth
Tachycardia
Blurred vision
Dithylin
Myorelaxant
Used to prevent reflex during tracheotomy
Should last 5-15 mins, if lasts longer = issue with B.esterase (aka pseudocholinoesterase)
Acetylcysteine
Depolymerizes sputum
Used to treat wet cough
Antidote for paracetamol
Antidote for MgS overdose
CaCl
Metronidazole
Candidiasis Chlamydia Lamblia Amoeba (Amoebic dysentry) Trichinosis H. Pylori
Mebendazole
Worm infections
Cotrimoxazole
Toxoplasmosis
Chingarine
Malaria
Unithiol
Heavy metal poisoning
Panagin
Corrects Vit K levels
Methotextrate
Cancers, tumors etc
Naloxone
Used for morphine toxicity
Narcotic analgesic
Promedol
Given to children instead of morphine
Morphine SE
Myotic pupil
Chyne stokes respiration (abnormal breath)
Aminazine
Treatment of alcoholic psychosis/schizophrenia
Droperidol
Used with phentanyl (puts you to sleep) for anesthesia (used for neuroleptanalgesia)
Diazepam
Antipsychotic drug
Activats GABA receptors (puts you to sleep)
Phenobarbital
Induces microoxidation of liver enzymes (Cytochrome P450) = causes haemolysis (e.g. Nasal haemorrhage)
Chronic vs Acute/Severe epilepsy
Chronic = Sodium Valporate Acute/Severe = Phenobarbital
Prednisolone
Medical form of cortisol
SE: Osteoporosis and stomach erosion
What inhibits atropine sulfate SE ?
Neostigmine and proserine
Epinephrine (adrenaline)
Used for anaphylactic shock during surgery
Metoprolol
Selective Beta 1 blocker
Used for arrhythmia, hypertension and angina
Reserpine
Given for hypertension
Glaucine
Non narcotic antitussive for dry cough
Heparin
Anticoagulant
Given parenterally
Purulent inflammation of gums
Candidiasis (aka ulcerative stomatitis)
Treat with metronidazole
Dimedrol SE
Sleepiness
Antihistamine drug
Loratadine
Antihistamine used to treat seasonal allergies (e.g. rhinitis)
No sleepy effect
Amlodipine
Long acting Ca channel blocker
Anti arrhythmic drug
Nitro glycerine MA
Decrease ATP (myocardial oxygen) consumption (Anti anginal drug)
Digoxin
Given for chronic cardiac insufficiency
Can cause material accumulation if self administered (stop taking drug if this occurs)
Corglycon
Given for acute heart failure
Furosemide and Hydrocholorthiazide
Causes forced diuresis
Cant use with digoxin (excretes K+)
Spironolactone
K+ sparing diuretic
Can use with digoxin
Given to a patient if they have increased aldosterone (secretes Na+) and peripheral edema
K+ permangenate
Oxidant antiseptic
Benzyl penicillin sodium and amoxicillin MA
Destroys microbial wall
Ciprofloxacin
Used to treat UTIs (e.g. gonorrhea)
NB: Contraindicated In children
Doxycycline/Tetracycline
Bacteriocidal antibiotic
Affects teeth
CI: Pregnancy and children (Teratogenic effects)
Isoniazid
Anti TB
SE= Polyneuruitis (optic nerve)
Gentomycin SE
Neuritis in vestibulocochlear n (hearing impairments)
Ketotifen
Adipose cell stabilizer prophylaxis (prevents allergy)
Glibenclamid
Treat insulin dependent diabetes and induced angiopathy
Butamin
Treat Type 2 diabetes (B cells stop producing insulin)
Stimulates B Cells
Rheumatoid arthritis treatment SE
Causes ulcers
SE of NSAIDs (Inhibits Cox1 = gastropathy)
Tachyphylaxis
Causes drug to stop working on the second day
Lobeline hydrochloride
Given for carbon monoxide poisoning
Any type of CNS injury
Use Nootropics to stimulate CNS
E.g. Ritalin
Ephedrine
Non selective adrenomimetic used to treat bronchial asthma
Given orally
Diuretics causing hypokalemia
Loop diuretics and thiazide
MA of Noradrenaline
Activation of alpha 1 adrenoreceptors
Fibrinolytic activators
remove thrombosis from MI
Pirenzepine
Given for gastritis with increase secretions
Adrenaline/glucose
Used to treat hypoglycemia in diabetics
Potentation
Some drugs increase the effect of other drugs
Summation
Drugs working together to make on effect
Organic nitrates
Given for angina/coronary heart disease
Contain nitrogen = increase methemoglobin
Aethimizolum
Newborns with asphyxia
Idiosyncrasy
Problem with enzymes (enzymopathy)
Mestatation solution
Activates alpha 1 receptors Causes mydriasis (pupil dilation)
Abstinence syndrome
Prolonged use of drug and sudden stop of it cause withdrawal symptoms
Isadrin
Treats bronchial asthma but increases angina (sternocardia)
Retinol acetate (Vit A)
Given for night blindness
Amicacin sulfate (Carbenicillin disodium)
Treats pseudomonadous infection
Bisacodyl
Chronic constipation
Morphinism
Addiction to morphine
Anticholinesterase drug
Proserine and neostigmine
Used to stimulate post operative peristalsis
Metoclopramide
Stops vomiting
Magnesium sulphate
Used for hypertensive crisis
Antihypertensive via IV
Given perorally
Vicasolum
Used as hemorrhage prevention
Sodium bromide
Sedative drug
SE: Cough and rhinitis
Narcotic analgesics
Agonists of opiate receptors
Ethanol
Used for methanol toxicity
Paracetamol
Has teratogenic effect during pregnancy
Dysbacteriosis
Imbalance of micro flora caused by antibiotics
Vasopressin
Given for diabetes inspidus
Acetylsalicinic acid
Has a disaggregating affect on isosorbide mononitrate
Benzylpenicillin sodium
I: Syphillis
MA: Blocks synthesis of peptidoglycan of microbal membrane
Adrenaline
Given for insulin overdose or shock
Lobeline hydrochloride
Restores breathing after carbon monoxide poisoning
Azithromycin
Resistant to penicillin
Ketotifen
Stabilizer of the adipose cells
Seasonal coryza
Antagonist of heparin
Protaminesulfate
Carbenicillin disodium
Used to treat Carbenicillin disodium
Sodium hydrocarbonate
Antacid (for indigestion)
SI = Stomach swelling
Proserin
Given for belladonna alkaloids poisoning
Also stimulates intestinal peristalsis
Natrium chloride
Given for Bromizm
Contrycal
Given for pancreatitis
Levomycetin
Given for bacterial dysentry if patient has anemia
Aminoglycosides SE
Hearing impairment
Vestibular impairment
Atropine
For organophosphate poisoning
Ketamine
Dissociative analgesia
SE: Hallucination
Digoxin vs Corglycon
D = Chronic CI C = Acute CI