Physiology Flashcards

1
Q

motor units allow what

A

simultaneous contraction

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2
Q

what is motor unit recruitment

A

stimulation of more motor units, stronger contraction

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3
Q

tension in the muscle is dependent on what? (3)

A

length of the muscle, thickness, frequency and summation of contraction

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4
Q

What is the relationship between AP and duration of resulting twitch

A

the AP is shorted than the resulting twitch

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5
Q

can cardiac muscle be tetanised?

A

no

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6
Q

why can cardiac muscle not be tetanised

A

the refractory period

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7
Q

two types of contraction exhibited by skeletal muscle

A

isotonic and isometric contraction

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8
Q

What is isotonic contraction

A

body movements; muscle tension remains constant

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9
Q

what is isotmetric contraction

A

support of objects in fixed positions, muscle tension develops at a constant

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10
Q

what is the relationship between velocity of muscle and load

A

as the load on muscle increases the velocity of muscle shortening decreases

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11
Q

4 examples of impaired skeletal muscle function

A

intrinsic disease of muscle, diseased NMJ, motor neurone disease, blocked input to motor units

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12
Q

stretch reflex is the most simple example of

A

Monosynaptic spinal reflex

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13
Q

the function of the stretch reflex

A

negative feedback that resists change in muscle length, this maintains optimal resting length of muscle

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14
Q

what is the muscle spindle

A

sensory receptor

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15
Q

when is the muscle spindle activated

A

by the muscle stretch reflex

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16
Q

what happens when the muscle spindle is stretched

A

increase in firing in the afferent neurones

17
Q

where do afferent neurones synapse

A

within the spinal cord with the alpha motor neurones

18
Q

how is the stretch reflex co-ordinated

A

relaxation of antagonist muscle

19
Q

what muscle is involved in the knee jerk reflex

A

Quadriceps femoris

20
Q

5 reflexes that can be tested with the tendon hammer

A

knee, ankle, biceps, triceps and brachioradialis

21
Q

what spinal nerves are involved in the biceps and brachioradialis reflex

A

C5-6

22
Q

what peripheral nerve is affected by the brachioradialis and triceps jerk

A

Radial

23
Q

what spinal nerves are involved in the knee jerk

A

L3 + 4

24
Q

what spinal nerves are involved in the ankle jerk

A

S1 + 2

25
Q

what spinal nerves are involved in the triceps jerk

A

C6 + 7

26
Q

what peripheral nerve is affected by the knee jerk

A

femoral nerve

27
Q

what peripheral nerve is affected by the ankle jerk

A

tibial nerve

28
Q

what peripheral nerve is affected in the biceps jerk

A

musculocutaneous nerve

29
Q

muscle spindles can also be called

A

intrafusal fibres

30
Q

extrafusal fibres are also called

A

ordinary muscle fibres

31
Q

where are muscle spindles found

A

within the belly of muscles

32
Q

sensory nerve endings on muscle spindles are called

A

annulospiral fibres

33
Q

efferent neurones that supply muscle spindles are called

A

gamma motor neurones

34
Q

what is the role of game motor neurones

A

adjust the level of tension in the muscle spindles

35
Q

differences between skeletal muscle fibres

A
  1. enzymatic pathways for ATP synthesis 2. resistance to fatigue 3. activity of myosin ATPase
36
Q

what are the type 1 fibres used for

A

prolonged low energy tasks; posture and walking

37
Q

what are the type 2a fibres used for

A

prolonged moderate energy tasks; jogging

38
Q

what are the 2x fibres used for

A

short term high intensity activities; jumping

39
Q

Investigations in neuromuscular disease

A

EMG, muscle enzymes, nerve conduction