Physio Hormones Flashcards
Salivary glands receive input from
PNS and SNS
BOTH enhance secretions (unique)
SNS: Celiac ganglia contribute to gut all the way up to distal colon, then at Distal,
the Sup/Inf Mesenteric ganglion take over
Where is CCK made
I cells of duodenum and jejunum
Where is Gastrin made
G cells of stomach
Where is Secretin made
S cells of duodenum
Where is GIP made
Duodenum and jejunum
Gastrin
Release of H in stomach, Gastric mucosa growth
CCK
Acts at various locations (Pancreas, gallbladder)
GIP
Increase insulin secretion
Slow stomach stuff: decrease emptying and H+ secretion
Secretin
Increase BICARB secretion
GIP released in small intestine as result of
Presence of breakdown of food stuff
(+) Insulin release
(-) gastric H secretion and emptying
Why can we respond so quickly to oral glucose?
Thx to GIP: Glucose dependent Insulinotropic Peptide
GI Paracrines (2)
Somatostatin
Histamine
Main GI Hormones (4)
Gastrin
CCK
Secretin
GIP
Main GI Paracrines (2)
Somatostatin
Histamine
Main GI Neurocrines (5)
Ach NE NO VIP GRP
BER (Basal electrical rhythm) originates in
Interstitial Cells of Cajal
“pacemaker cells”
(in Myenteric plexus)