Clin Lab Med Flashcards
Lupus
Anti-ds DNA
Anti-Sm (smith)
RA
Anti-CCP*
RF
Sjogren Syndrome
Anti-Ro
Anti-La
Systemic Sclerosis
ACA
Anti-Scl-70
PMR
ESR
CRP
Ankylosing Spondy
HLA-b27
> 2,000 WBC in effusion
Considered inflammatory
<2,000 WBC in effusion
Non-inflammatory
Septic joint classification
> 20,000
WBC differential in Joint effusion
> 75% Neutrophils: Septic
Gout
MSU
Negatively birefringent and Needle shaped
Pseudogout
CPPD
Positively birefringent and Rhomboid shaped
Lupus
Bilateral hands/feet/knees pain and swelling Raynaud phen Malar rash Pleuritic, sharp CP Discoid rash Mouth ulcers
RA
SPARES DIPs
AM stiffness >1 hour
(no muscle pain)
Sjogren Syndrome
Sicca complex: dry eyes and mouth
Cavities
Diffuse myalgia and arthralgia
Systemic Sclerosis
Thickening and tightening of skin on hands and face
Esophageal issues- difficult to swallow
Telangiectasias
Raynaud
Systemic Sclerosis
Limited- CREST
ACA lab
Calcinosis, Raynaud, Esophogeal dysfx, Sclerodactylyl, Telangiect
PMR
Acute onset of PROXIMAL pain Difficulty ADL- getting dressed "Gel phenomenon" Decreased ROM Tx: PROMPT IMPROVEMENT with low dose steroids
Ankylosing Spondy
Ongoing low back pain Progressive stiffness Exercise helps Plantar fasciitis "Bamboo spine & Sacroiliitis"
Gout
FEVER
prime rib, cocktails, drinking night before triggers
Pseudogout
No fever
X Ray: Chondrocalcinosis