Phys 2 Pulmonary Blood Flow

Question 1

extra-alveolar capillaries?

O2/CO2 profile?

blood from where?

return to heart where?

what does that cause?

Answer 1

Question 2

Blood pressure and pulmonary blood pressure

what is the equation?

Answer 2

Question 3

difference between values for blood pressure and pulmonary pressure?

Answer 3

Question 4

Pulmonary vascular resistance

Determined by?

Answer 4

Question 5

PVR during exercise?

Answer 5

Question 6

PVR and lung volume?

Answer 6

Question 7

Why pass out while standing a long time?

how will not locking knees help?

Answer 7

• Here gravity works on the blood in our bodies. with gravity blood pressure in our legs is increased compared to that of the heart or brain
• same can happen in the lungs

Question 8

Regional blood flow in the lungs

Apex of the lung

Answer 8

Question 9

Regional blood flow in the lungs

middle region of the lung

Answer 9

Question 10

Regional blood flow in the lungs

Base of the lung

Answer 10

Question 11

Chemical modulators of pulmonary blood flow?

Answer 11

Question 12

Why do we want to keep alveoli “dry”?

Answer 12

• alveoli allow oxygen to move from air to blood. Oxygen is not terribly water soluble.
• If capillaries leaked water into alveoli it would impair ability of oxygen to cross blood

Question 13

What controls how much fluid moves from capillary to the lung?

Answer 13

Starling forces

Question 14

What are the two general pressures at work with starling forces?

Answer 14

• Hydrostatic pressure
• Oncotic pressure

Question 15

Hydrostatic pressure?

where are these

Answer 15

(fluid pushing against the tissue or walls of the capillary)

• The capillary (P_c)
  
  • blood pressure in capillary trying to push fluid into alveoli
• The tissue (P_t)
  
  • in rest of body this pushes fluid into capillary

Question 16

hydrostatic pressure in the lungs
what happens to P_tissue in the lungs?

what causes this?

Answer 16

Question 17

Oncotic pressure

where?

Answer 17

(think osmotic pressure of the fluids involved)

• The plasma (capillary oncotic pressure) π_c
  
  • tries to pull water into the capillary
• The tissue (tissue oncotic pressure) π_Tissue
  
  • tries to pull water into the alveolus

Question 18

Forces moving water from capillary to alveolus?

Answer 18

Question 19

Forces moving water from alveolus to capillary?

Answer 19

Question 20

Starling forces equation for the lung?

what is the biggest force?

Answer 20

P_c (hydrostatic pressure in the capillary)is the largest single force

Question 21

Net result of adding up starling forces is favor net filtration where?

this good or bad?

Answer 21

favors net filtration of fluid into the alveoli

(this is bad)

Question 22

With a net force into alveoli

fluid is bad for gas exchange so what do we do?

Answer 22

Lymphatics

Question 23

Metabolic functions of the lung

(Blood pressure)

start with what?

end product?

intermediates?

where are things produced?

Answer 23

Angiotensin can raise blood pressure through aldosterone

Question 24

What can ACE inhibitors do?

what does ACE stand for?

Answer 24

Question 25

Metabolic functions of the lung

Lead to production of what?

whats removed

Answer 25