EMB 2 Respiratory Embryology Flashcards
Respiratory system endoderm
What forms the epiglottis?
arches 3/4 specifically 4
Hypobranchial eminence
explain arytenoid swellings
Mesenchyme (endodermal covering)
derived Neural Crest
The endoderm will proliferate and fill up the space.
recanalization (apoptosis) will open again
what is recanalization?
when does it happen?
what does it create?
10th week
creates vocal and vestibular folds
apoptosis to open the proliferated endoderm
laryngotracheal groove
location?
germ layer?
Endoderm
Ventral wall of pharynx 6th arch
Laryngeal atresia
Laryngeal webs
Laryngomalacia
Trachea made up of what?
Tracheoesophageal Fistula?
Esophageal atresia?
what went wrong?
when?
Bronchi and lungs
development what weeks does what develop?
Bronchopulmonary segment?
get air into lungs
24 weeks 17 orders of branches, terminal bronchioles
First two stages of lung development
weeks?
whats formed?
survival?
3rd and 4th stage of lung development
what can happen now?
what cells are present?
survival?
stages of lung development recap
Fetal breathing movements?
why do we need to do it?
at birth?
Oligohydramnios
what is it?
what can it cause?
when is the highest risk?
What disease? What point went wrong?
patient arrives with
Tachypnea
nasal flaring
retractions (muscle twiching)
grunting
cyanosis
X-ray shows
Hyaline membrane disease
from lack of surfactant
(defect in terminal sac phase)
x-ray has a cloudy ground glass appearance and low lung volumes
Respiratory distress and cyanosis
lung hypoplasia
Seen in physical examination?
diagnosis?
Mom had polyhydramnios (too much amniotic fluid)
infant w/ excessive secretions that cause drooling, choking, coughing, gaggling, respiratory distress and inability to feed.
What embryological mechanism explains this?
what week?
Tracheoesophageal fistula
Tracheal esophageal folds and septum did not fold correctly in
WEEK 5
