Pheochromocytoma Flashcards
1
Q
What is a pheochromocytoma?
A
Rare catecholamine secreting tumour
2
Q
What is the 10% rule?
A
- 10% bilateral
- 10% familial
- 10%malignant
- 10% Extra-adrenal
3
Q
What is a pheochromocytoma associated with?
A
- MEN2
- Neurofibromatosis
- Von hippel-Lindau syndrome
4
Q
What are the main presentations of a pheochromocytoma?
A
Pain
Perspiration
Palpatations
5
Q
How else can a pheochromocytoma present?
A
• Pressure • Pain-headache • Perspiration- sweating • Palpitations • Pallor • Paroxysmal AF • Tremor Hypertension (possibly sustained)
6
Q
How does the hypertension present in pheochromocytoma?
A
Sustained hypertension
7
Q
What is the main diagnostic test for pheochromocytoma?
A
24 hour urinary collection of metanephrines
8
Q
What is the management of a pheochromocytoma?
A
First: Alpha blocker
Then: Beta blocker
Definitive: Adrenalectomy
9
Q
What is required before an adrenalectomy?
A
Alpha blocker and beta blocker
10
Q
What alpha blocker would you give for pheochromocytoma?
A
Phenoxybenzamine
11
Q
What beta blocker would you give for pheochromocytoma?
A
Propranolol
