Phenoxy derivatives of fatty acids (Herbicide) Flashcards
Source
Accidental ingestion of concentrates
Grazing or access to freshly sprayed pastures or lawns
Use for
Herbicide Recommended concentration on forages
Effects on plants:
Alter their metabolism which increases their toxicity by incrasing accumulation of nitrate and cyanide.
Improve palatability of poisonous plants
Properties
Not stable in enviroment
Not degraded my rumen microflora and doesnt alter it.
Irritant to
GI mucosa
Most susceptible animals
Cattle and dogs
Most sensitive species
Dogs
Absorbed in
GI tract
Poorly absorbed in
skin
Distributed:
all over the body
Excreted in
urine
MoA
GI tract irritation
Dogs: skeletal muscle membranes affected
Clinical signs are mainly
GI and NM
Lesions
GI damage
Liver and kidney degeneration
Rumen stasis with ingested food
lab dx
Chemical analysis: forage, water, kidney, liver, urine, stomach contents, feces
Elevated AP, LDH, CPK
