Pharmocology Unit 5 Flashcards

1
Q

What is the location of the thalamus?

A

Located deep within the brain, superior to the hypothalamus.

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2
Q

What are the functions of the thalamus?

A

Relays sensory and motor signals to the cerebral cortex, regulates consciousness, sleep, and alertness, plays a role in processing emotions and memory, and acts as a filter for incoming sensory information.

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3
Q

What is the location of the cerebrum?

A

The largest part of the brain, located in the upper portion of the cranial cavity, divided into two hemispheres (left and right).

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4
Q

What are the functions of the cerebrum?

A

Responsible for higher-level cognitive functions, controls voluntary motor functions, interprets sensory information, language processing (primarily in the left hemisphere), personality, and conscious thought.

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5
Q

What is the location of the cerebellum?

A

Located at the back of the brain, beneath the cerebrum.

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6
Q

What are the functions of the cerebellum?

A

Coordinates voluntary motor movements, posture, and balance; plays a role in motor learning and fine motor control; helps with maintaining equilibrium.

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7
Q

What is the location of the brain stem?

A

Connects the cerebrum and cerebellum to the spinal cord, comprised of the midbrain, pons, and medulla oblongata.

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8
Q

What are the functions of the brain stem?

A

Controls essential involuntary functions such as breathing, heart rate, and blood pressure; relays information between the brain and spinal cord; plays a role in sleep-wake cycles.

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9
Q

What is the location of the medulla oblongata?

A

The lowest part of the brain stem, continuous with the spinal cord.

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10
Q

What are the functions of the medulla oblongata?

A

Controls vital autonomic functions, including heart rate, respiration, and blood pressure; reflex centers for vomiting, coughing, sneezing, and swallowing; relays nerve signals between the brain and spinal cord.

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11
Q

What is the location of the pons?

A

Located above the medulla oblongata and below the midbrain, within the brain stem.

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12
Q

What are the functions of the pons?

A

Relays signals between the cerebrum and the cerebellum; involved in controlling respiration, sleep, and arousal; contains cranial nerve nuclei.

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13
Q

What is the location of the hypothalamus?

A

Located below the thalamus, within the diencephalon.

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14
Q

What are the functions of the hypothalamus?

A

Regulates body temperature, hunger, thirst, and sleep-wake cycles; controls the autonomic nervous system; produces hormones that control the pituitary gland; plays a key role in emotional responses.

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15
Q

What is Depression?

A

A mood disorder that causes persistent feelings of sadness, loss of interest, and can interfere with daily life.

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16
Q

What are the signs and symptoms of Depression?

A

Persistent sad, anxious, or ‘empty’ mood. Loss of interest or pleasure in activities. Changes in appetite or weight. Sleep disturbances (insomnia or hypersomnia). Fatigue or loss of energy. Feelings of worthlessness or excessive guilt. Difficulty concentrating, remembering, or making decisions. Thoughts of death or suicide.

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17
Q

What are the drug therapies for Depression?

A

Selective serotonin reuptake inhibitors (SSRIs) (e.g., sertraline, fluoxetine). Serotonin-norepinephrine reuptake inhibitors (SNRIs) (e.g., duloxetine, venlafaxine). Tricyclic antidepressants (TCAs) (e.g., amitriptyline, nortriptyline). Monoamine oxidase inhibitors (MAOIs) (e.g., phenelzine, tranylcypromine).

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18
Q

What is Mania?

A

A state of abnormally elevated mood, increased energy, and impulsive behavior.

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19
Q

What are the signs and symptoms of Mania?

A

Elevated mood (euphoria) or irritability. Increased energy and activity. Racing thoughts and rapid speech. Impulsive or reckless behavior. Decreased need for sleep. Grandiose ideas or inflated self-esteem. Distractibility.

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20
Q

What are the drug therapies for Mania?

A

Mood stabilizers (e.g., lithium, valproic acid, lamotrigine). Antipsychotics (e.g., risperidone, olanzapine).

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21
Q

What is Parkinson’s Disease?

A

A progressive nervous system disorder that affects movement.

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22
Q

What are the signs and symptoms of Parkinson’s Disease?

A

Tremor (shaking), often in the hands. Bradykinesia (slowed movement). Rigidity (stiffness of the limbs and trunk). Postural instability (impaired balance and coordination). Speech changes. Loss of automatic movements (e.g., blinking, smiling).

23
Q

What are the drug therapies for Parkinson’s Disease?

A

Levodopa/carbidopa. Dopamine agonists (e.g., pramipexole, ropinirole). MAO-B inhibitors (e.g., selegiline, rasagiline). COMT inhibitors (e.g., entacapone).

24
Q

What is Anxiety?

A

A feeling of worry, nervousness, or unease, typically about an imminent event or something with an uncertain outcome.

25
What are the signs and symptoms of Anxiety?
Excessive worry or fear. Restlessness or feeling on edge. Muscle tension. Difficulty concentrating. Sleep disturbances. Rapid heartbeat or palpitations. Sweating or trembling.
26
What are the drug therapies for Anxiety?
SSRIs and SNRIs (also used for depression). Benzodiazepines (e.g., lorazepam, alprazolam) (for short-term use). Buspirone.
27
What is Bipolar Disorder?
A mental health condition that causes extreme shifts in mood, energy, activity levels, concentration, and the ability to carry out day-to-day tasks.
28
What are the signs and symptoms of Bipolar Disorder?
Episodes of mania or hypomania (less severe mania). Episodes of depression. Mixed episodes (both mania and depression symptoms).
29
What are the drug therapies for Bipolar Disorder?
Mood stabilizers (e.g., lithium, valproic acid, lamotrigine). Antipsychotics (e.g., risperidone, quetiapine). Antidepressants (used with caution, often with a mood stabilizer).
30
What is Schizophrenia?
A chronic brain disorder that affects a person's ability to think, feel, and behave clearly.
31
What are the signs and symptoms of Schizophrenia?
Positive symptoms (e.g., hallucinations, delusions, disorganized thinking). Negative symptoms (e.g., reduced emotional expression, social withdrawal). Cognitive symptoms (e.g., impaired memory, difficulty concentrating).
32
What are the drug therapies for Schizophrenia?
Antipsychotics (e.g., risperidone, olanzapine, quetiapine, aripiprazole).
33
Who can diagnose and create a treatment plan for these conditions?
Only a licensed medical professional.
34
What are the basal ganglia?
A group of cell bodies (gray matter) within the white matter of the cerebrum that helps control body movement.
35
What is the function of the cerebellum?
Part of the brain that coordinates body movements and posture and helps maintain body equilibrium.
36
What does the cerebral cortex do?
Uppermost layers of the cerebrum involved in sensory perception, voluntary motor control, and all higher intellectual abilities.
37
What is the cerebrum?
Largest and uppermost part of the brain that is divided into right and left cerebral hemispheres.
38
What is an electroencephalogram (EEG)?
A surface recording of the electrical brain.
39
What is the role of the hypothalamus?
Part of the diencephalon that regulates functions such as body temperature, water balance, appetite, and the pituitary gland.
40
What is the limbic system?
Neural pathway connecting different brain areas involved in regulation of behavior and emotion.
41
What does the medulla oblongata control?
Lower part of the brainstem that controls cardiac, vasomotor, and respiratory functions.
42
What is the function of the pons?
Part of the brainstem that serves as a relay station for nerve fibers traveling to other brain areas; also involved in sensory and motor functions.
43
What is the reticular formation?
Network of nerve fibers that travel throughout the central nervous system that regulates the level of wakefulness.
44
What does the thalamus do?
Uppermost part of the diencephalon that regulates sensory and motor impulses traveling to and from the cerebral cortex.
45
What is automatism?
Drug-induced confusion that can cause increased drug consumption.
46
What is a barbiturate?
CNS depressant drug possessing the barbituric acid ring structure.
47
What is a benzodiazepine?
Class of drugs used to treat anxiety and sleep disorders.
48
What does GABA stand for?
Gamma-aminobutyric acid, an inhibitory neurotransmitter in the CNS.
49
What is a hypnotic?
Drug used to induce and maintain sleep.
50
What is a nonbarbiturate?
Refers to sedative-hypnotic drugs that do not possess the barbituric acid structure, such as benzodiazepines and related drugs.
51
What is NREM sleep?
Stages of sleep characterized by nonrapid eye movement (NREM).
52
What is REM sleep?
Stages of sleep characterized by rapid eye movement (REM) and dreaming.
53
What is a sedative?
Drug used to produce mental relaxation and to reduce the desire for physical activity.