Pharmocology Flashcards
What are the A drugs prescribed for hypertension?
A
-Ace inhibitors
-Ramopril
-Stops ACE enzyme from working
-Dry cough, fatuigye, headaches
-Angiotensin 2 blockers
-Irbarstaten
-prevents conversion of ANG1 to ANG 2
-Dizziness and swelling
What are the B drugs prescribed for hypertension?
B
Beta Blockers
Propanol
Bind to beta receptors and stop them from responting to adreanline so preventing sympathetic nervous system
Bradycardia and low blood pressure
What are the C drugs prescribed for hypertension?
C
Calcium channel blockers
Amlodapine
Blocks the calcium channels and causes less contractility in the heart
Muscle aches and impotentce
What are the D drugs prescribed for hypertension?
D
Diuretics Bumetanide
Reduce water content of the blood
Increased urination
what are biguanide drugs for diabeties: drug name, mechanism , side effects
Metformin
Reduce hepatic glucose production
Decrease intestinal absorption of glucose
Increase glucose uptake and utilisation in peripheral tissue
GI disturbances - abdo pain, anorexia, diarrhoea, nausea, weightloss, sometime lactic acidocis in renal failure, hepatic diseaseor heart faliure
what are teh sulfonylurea for diabeties: drug name, mechanism , side effects
Gliclazide
Glipizide
Stimulate B cells to secrete insulin
CAN CROSS PLACENTA AND ENTER BREAST MILK!!
Hypoglycaemia
Weight gain
what are teh DPP4 inhibitors for diabeties: drug name, mechanism , side effects
Sitagliptin
Inhibit DPP4 so increase the effect of incretins GLP1 and GLP which augment insulin
Doesn’t cause weight gain or weight loss
wjat are gloxane for diabeties: drug name, mechanism , side effects
Pioglitazone
Enhance fatty acid uptake and glucose
Fluid retention
Weight gain
what are SGTL2 for diabeties: drug name, mechanism , side effects
Dapagliflozin, canagliflozin
Cause the body to urinate out more glucose
Yeast infections by candida albicans (this is thrush) due to the excess sugar in the area