Pharmocology Flashcards

1
Q

What are the A drugs prescribed for hypertension?

A

A
-Ace inhibitors
-Ramopril
-Stops ACE enzyme from working
-Dry cough, fatuigye, headaches
-Angiotensin 2 blockers
-Irbarstaten
-prevents conversion of ANG1 to ANG 2
-Dizziness and swelling

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2
Q

What are the B drugs prescribed for hypertension?

A

B
Beta Blockers
Propanol
Bind to beta receptors and stop them from responting to adreanline so preventing sympathetic nervous system
Bradycardia and low blood pressure

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3
Q

What are the C drugs prescribed for hypertension?

A

C
Calcium channel blockers
Amlodapine
Blocks the calcium channels and causes less contractility in the heart
Muscle aches and impotentce

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4
Q

What are the D drugs prescribed for hypertension?

A

D
Diuretics Bumetanide
Reduce water content of the blood
Increased urination

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5
Q

what are biguanide drugs for diabeties: drug name, mechanism , side effects

A

Metformin

Reduce hepatic glucose production
Decrease intestinal absorption of glucose
Increase glucose uptake and utilisation in peripheral tissue

GI disturbances - abdo pain, anorexia, diarrhoea, nausea, weightloss, sometime lactic acidocis in renal failure, hepatic diseaseor heart faliure

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6
Q

what are teh sulfonylurea for diabeties: drug name, mechanism , side effects

A

Gliclazide
Glipizide

Stimulate B cells to secrete insulin

CAN CROSS PLACENTA AND ENTER BREAST MILK!!

Hypoglycaemia
Weight gain

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7
Q

what are teh DPP4 inhibitors for diabeties: drug name, mechanism , side effects

A

Sitagliptin

Inhibit DPP4 so increase the effect of incretins GLP1 and GLP which augment insulin

Doesn’t cause weight gain or weight loss

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8
Q

wjat are gloxane for diabeties: drug name, mechanism , side effects

A

Pioglitazone

Enhance fatty acid uptake and glucose

Fluid retention
Weight gain

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9
Q

what are SGTL2 for diabeties: drug name, mechanism , side effects

A

Dapagliflozin, canagliflozin

Cause the body to urinate out more glucose

Yeast infections by candida albicans (this is thrush) due to the excess sugar in the area

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