pharmo Flashcards

1
Q

Which of the following statements most accurately describes the action of ACE inhibitors on the glomerular filtration pressure?

A

vasodilation of the efferent arteriole

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2
Q

normal stroke volume range

A

55-100

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3
Q

factors affecting stroke volume

A

Cardiac size
Contractility
Preload
Afterload

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4
Q

how do you calculate stroke volume

A

It is calculated by subtracting the end systolic volume from the end diastolic volume.

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5
Q

what integers with the absorption of ACEI reducing its therapeutic effect?

A

Antacids interfere with the absorption of ACE-inhibitors, reducing its therapeutic effect. Low dose aspirin is safe to use in patients on ACE-inhibitors.

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6
Q

what drugs are zero order pharmokinetics

A

Key examples of zero-order drugs are salicylates (aspirin), phenytoin, ethanol, and fluoxetine.

Amitriptyline, ampicillin, apixaban and atenolol all display first-order kinetics.

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