Pharmacy Definitions Flashcards

1
Q

What form is used to prescribe a medication?

A

DD 1289

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2
Q

What form is utilized to prescribe more than one medication?

A

NAVMED 6710/6 (Polyprescription)

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3
Q

What information should be on the Prescription?

A
  1. Patient’s name
  2. Date
  3. Patients DOB
  4. Full name of the drug, form of the drug, dosage, quantity
  5. Directions for the patient
  6. Signature of provider
  7. Refill Authorization
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4
Q

What are the principles of pharmacology?

A
  1. Factors that affect the actions of drugs
  2. Factors that affect drug reactions
  3. Types of drug interactions
  4. Factors influencing drug response interactions
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5
Q

What is pharmacokinetic?

A

Activities of the drug after it enters the body. (movement)

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6
Q

What is absorption?

A

Transfer of drug from body fluids to body tissues

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7
Q

what is active absorption?

A

Molecules such as protein or enzymes actively moves the drug across the membrane. (Form of ATP)

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8
Q

What is passive absorption?

A

Diffuse across the membrane, from higher to lower area of cocentration. (Water Soluble Drugs)

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9
Q

What isw pinocytosis?

A

Cells engulf the drug particle across the membrane. (Think Pacman)

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10
Q

What is bioavailability?

A

Percentage of the administered drug dose that reaches the systemic circulation

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11
Q

What are some factors that affect bioavailability?

A
  1. Form of the medication
  2. Route of administration
  3. Changes in liver metabolism
  4. Gi mucosa and motility
  5. Food and Drugs
  6. Solubility
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12
Q

What is solubility?

A

Drugs that are fat soluble are absorbed faster than water-soluble drugs

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13
Q

What is a therapeutic effect?

A

Drug levels in blood to produce the desired effect

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14
Q

what is metabolism?

A

Chemical reaction where the liver converts drugs to inactive compounds

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15
Q

Where does metabolism take place in the body?

A

Liver, Kidneys, Lungs, Plasma, Indestinal Mucosa

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16
Q

What is execretion?

A

Elimination of drugs from the body

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17
Q

What is half-life?

A

Time required for the body to eliminate 50% of the drug

18
Q

What is pharmacodynamic?

A

Drug’s actions and effects within the body

19
Q

What is a physical dependence?

A

Compulsive need to use a substance repeatedly to avoid mild to severe withdrawal symptoms

20
Q

What is psychological dependence?

A

Compulsion to use a substance to obtain a pleasurable experience

21
Q

What is pharmacogenetic disorder?

A

Genetically determined abnormal response to normal dose of a drug

22
Q

What is a receptor?

A

Specialized macromolecule that binds to the drug molecule, altering the function of the cell and producing the therapeutic response

23
Q

What is alterations in Cellular environment?

A

Drug that alters cellular function can increase or decrease the physiologic functions of the cell. (Ex: Increased heart rate, decreased blood pressure)

24
Q

What is a therapeutic response?

A

Alteration of the cell to achieve the desired response

25
Q

What is an agonist?

A

Drug that binds wiht a receptor to produce the therapeutic response. (Binds to dopamine receptors)

26
Q

What is an antagonist?

A

Drug binds to receptor stronger than the agonist thus producing no pharmacologic effect.
(Ex: Narcan is an antagonist to Morphine) (reverses the action)

27
Q

What is an adverse reaction?

A

Undesirable drug effect

28
Q

What is an allergic reaction?

A

Drug reaction that occurs because the individual’s immune system views the drug as a foreign substance

29
Q

What is drug idiosyncrasy?

A

Any unusual or abnormal reaction to a drug that a patient has, that doesn’t occur in the vast majority of patients taking the same drug

30
Q

What is Cumulative drug effect?

A

Drug effect that occurs when the body has not fully metabolized a dose of the drug before the next dose is given

31
Q

What is toxic?

A

Harmful drug effect if it is delivered in high dose or when blood concentration levels exceed therapeutic levels

32
Q

What is a pharmacogenetic reaction?

A

Inherited traits that cause abnormal metabolism of the drug

33
Q

What is pharmeceutic phase?

A

Dissolution of a drug. Usually applying to the breakdown of tablets

34
Q

What is addictive drug reaction?

A

Reaction that occurs when the combined effect of 2 drugs is equal to the sum of each drug given alone. (Think addition)

35
Q

What is syngerism?

A

Drug interaction that occurs when drugs produce an effect that is greater than the sum of their separate actions. (Think multiplication)

36
Q

What is an antagonist drug reaction?

A

When one drug interferes with the action of another, causing neutralization or a decrease in the effect of one drug

37
Q

What is drug-food interaction?

A

Drugs given orally, food may impair or enhance it’s absorption

38
Q

What are some factors that influence drug response?

A
  1. Age
  2. Weight
  3. Gender
  4. Disease
  5. Route of aministration
    6.
39
Q

What is teratogen?

A

Substance that may produce physical or functional defects in a human embryo or fetus

40
Q

What are the drug ratings in pregnancy?

A
A = No Risk
B = no evidence of risk
C = Risk cannot be ruled out
D = Positive evidence of risk
X = Contraindicated in Pregnancy