pharmacology toxicities and SEs Flashcards
Acetaminophen toxicity treatment
N-acetylcysteine - replenishes glutathione
Salicylates toxicity treatment
NaHCO3 (alkalinize urine)
dialysis
ampphetamines (basic) toxicity treatment
NH4Cl (acidifies urine)
acetylcholinesterase inhibitors
organophosphates toxicity treatment
atropine, pralidoxine (induces synthesis of new AChE)
antimuscarinic, anticholinergic agents toxicity treatment
physostimine salicylate, control hyperthermia
beta blocker toxicity treatment
glucagon - increases cAMP
digitalis toxicity treatment
normalize K+
lidocaine
anti-dig Fab fragments
Mg2+ (magnesium)
iron toxicity treatment
deferoxamine
deferasirox
lead toxicity treatment
penicillamine
cyanide toxicity treatment
nitrite + thiosulfate
hydroxocobalamin
methemoglobin treatment
methylene blue
vitamin C
CO toxicity treatment
100% O2, hyperbaric O2
methanol, ethylene glycol (antifreeze) toxicity treatment
fomepizole > ethanol, dialysis
opioids toxicity treatment
naloxone/ naltrexone
benzodiazepines toxicity treatment
flumazenil
TCAs toxicity treatment
NaHCO3 (plasma alkinization)
heparin toxicity treatment
protamine
warfarin toxicity treatment
vitamin K
fresh frozen plasma
tPA, streptokinase, urokinase toxicity treatment
aminocaproic acid
theophylline toxicity treatment
beta-blocker