Pharmacology practical Flashcards
name of dosage form
Useful for
Orodispersible film
Pediatric and geriatric
This dosage from is?
give the two types
Rectal enema
Retention enema
Evacuant enema
Name dosage form a and B and give two disadvantages
Discus and nebulizer
inaccurate dosing
drugs may irritate epithelium
name of these two inhaling devices
Spinhaler
Discus
name the devices
neubilizer
Atomizer
mention this route of admin
Advantage of this route
Enumerate two drugs administered like this
Topical and transdermal patch
Prolong blood level with minimal fluctuation avoid 1st pass effect
Nitroglycerine and fetanyl patch
What is the site of the action of the unknown?
Which type of mydriasis this unkown produce?
Mention the effect of the unkown on IOP. Explain?
muscurinic receptros blockers
passive mydriasis
due to mydriasis and cycloplegia
muscurinic receptors blockers
passive mydriasis
increase in IOP due to mydriasis and cycloplegia
Stimulation of mucarinic receptor on the constrictor pupillae muscle
Pilocarpine and physostigmine
Contraction –> accommodation
amphetamine
alpha1-receptor the dilator papillae muscle
ocular blood vessels –> vasoconstriction —> decongestion
Muscurinic receptors agonist M3 and nicotinic receptors
Carbachol and all anticholinesterases
Decrease IOP due to opening of canal of Schlemm because of miosis
What could be the unknown?
Identity the site of action of the unknown?
What is the type of antagonism in curve?
Ganglion stimulant like LS
Nicotinic receptor
Depolarizing antagonism
Mention the site of action of the unknown
give 2 examples for the unknown
Atropine is an example of a _____ antagonist
Muscarinic receptors
Ach, carbachol
Competitive
The unknown could be ____or_______
Explain:
The muscarinic blocker, atropine could block NSD effect.
Muscarinic agonist or nicotinic agonist
Nicotinic agonist mediate their effects indirectly through muscarinic receptors
what is the site of action of the unknown
Mention 2 examples for the unknown
what is the type of antagonism in the curves?
Beta-1 receptors
Adrenaline, isoprenaline
Competitive
What is the site of the action of the unknown?
What kind of drug interaction exists between the unknown and cimetidine?
H2 receptors
Competitive antagonism
What is the site of action of the unkown?
What is the type of antagonism?
Mmention other drug acting by another type of antagonism mechanism?
Nicotinic agonist
Competitive antagonism
Depolarizing GB
Mention two examples of the unkown
Mention the site of action of the unkkown
Mention 2 different types of anatagonism in the curve
Any parasympathomimetic drug as Carbachol or pilocarine
Acts on muscarnic recptors
Competitive and depolarizing antagonism
what couldthe unkown be
What is the mechanism of action of mecamylamine
Angiotensin II
Competitive nicotinic receptor blocker
What could be the unkown
If you want to replace both phentolamine and propranolol by one drug you can administer?
Adrenergic alpha and beta stimulants like adrenaline
Labetalol
What is the site of action of the unkown?
What is the mechanism of the HYPER-tensive effect of the unkown drug in large dose?
Muscarininc and nicotinic receptors
Stimulant of the nicotininc receptor__> release adrenaline —> stimulate alpha receptor —> VC
The hypotensive effect of the unkowns is through
Give 2 examples o the unkown
Action on B2 receptors
Salbutamol, isoprenaline
What is the site of action of the unknown?
WHat is teh effect of the unkown on heart rate?
What could be unkown if its hypertensive effect is reversed by phentolamine?
Alpha receptor agonist
Bradycardia
Adrenaline
prescription for urgent situations (part 1)
Hypertensive emergency with pulmonary edema
Acute anginal attack
Acute attack of bronchial asthma
Acute attack of migraine headache
Anaphylactic shock
furosemide ampule 20 mg
Nitroglycerin tablet 0.5 mg
Salbutamol inhaler
Sumatriptan tablets 50 mg
Adrenaline ampoule 0.5 mg
Parasympathetic depressant for treatment of intestinal colic
Hyoscine butyl bromide Tablets 10 mg (after eating 3 times per day)
Autacoid prescriptions
Non-sedating anti histamine used in allergy
Serotonin agonist to stop vomiting in chemo
Cetirizine tablet 10 mg
Ondansetron ampoule 8 mg
Diuretic perscriptions
Lower limb edema
for mild hyper tension
Bumetanide tablet 1 mg
Hydrochlorothiazide tablet 25 mg
Cardiovascular prescriptions
Ca channel blocker for hypertension
Angiotensin converting enzyme inhibitor for hypertension
Amlodipine tablet 10 mg
Lisinopril tablet 10 mg
Nitrates for prophylaxis of angina
B-adrenergic blocker for angina pectoris
Anti-platelet drug for prophylaxis of angina pectoris with peptic ulcer patient
Isosorbide mononitrate capsules 25 mg
Antenolol tablets 100 mg
Clopidogrel tablets 75 mg
