Patho Slides

Question 1

Answer 1

Myocardial scar

Section in myocardium
Area of scar tissue
Adjacent cardiac muscles are red and slightly atrophic

Question 2

Answer 2

Arterial thrombus

Transverse section in blood vessels

Lumen is occluded by a thrombus between lines of Zahn which is made of fibrin entangling

Question 3

Answer 3

Atheroma, small artery

Section in small artery

The empty clefts were occupied by cholesterol
Internal elastic lamina is thinned and so is the media
Thickened subendothelial CT with needle/spindle shaped

Question 4

Answer 4

Lobular Pneumonia

Section in lung

Alveolar spaces contain network fibrin entangling RBCS and some macrophages
Alveolar wall are thickened and show edema and congestion

Acute nonsuprative fibrinous inflammation

Question 5

Answer 5

Chronic venous congestion in lung

Lung section

Alveolar wall are thickened due to interstitial edema and congested
Alveolar spaces contain transudate, entangling red cells and hemosiderin granules (the BROWN CELL)

Question 6

Answer 6

Infarction lung

Lung

The infract show atrophic alveolar wall appears as thin fibrous septa
Rest of lung shows chronic venous congestion

Question 7

Answer 7

Miliray TB in lung

small tubercles scattered in lung tissue
Each tubercle shows minimal central caseation

Arrow points at giant cells

Question 8

Answer 8

Acute suppurative appendicitis

The mucosa, submucosa show edema, congested capillaries and exudate
Lumen of the appendix contains fibrin network entangling mucosal cells

Question 9

Answer 9

Fibrinous peritonitis small intestine

Peritoneum shows shed serosal cell covered by fibrin
Subserosal CT shows edema, congestion and acute infiltrate

Question 10

Answer 10

Adenoma (intestine)

Benign tumor formed of proliferated acini lined by columnar mucin secreting cells
Some show pseudo-stratification
Vascular CT is found between gland

precancerous

Question 11

Answer 11

Adenocarcinoma colon

Showing malignant gland
Irregular in shape, and in lumen, lined in anaplasic-like cells
Invading colon

Question 12

Answer 12

Bilharziasis rectum

section in colonic mucosa

Showing bilharzial granuloma. Many bilharzia ova with reflective shell.
Ova are surrounded by bilharzial reaction (lymphocytes plamsa, fibrosis, giant cells

Non precancerous

Question 13

Answer 13

Bilharzial polyp

Section in colon

Showing core showing fresh degenerated by bilharzial reaction (lymphocytes, plasma cell, macrophage)
Hyperplastic covering mucosa

Not precancerous

Question 14

Answer 14

Fibrinous peritonitis

In liver

covering peritoneum shows shedded serosal cells and covered by network fibrin
Has acute inflammatory infiltrate
Subserosal CT shows edema, congested capillary and inflammation

Question 15

Answer 15

Bilharzial periportal fibrosis

Section in liver

Portal tract is side fibrinous due to bilharzial ova and is surrounded by bilharzial reaction (lymph, plasma cells, macrophage)

Question 16

Answer 16

Chronic venous congestion of liver

central veins and sinisuoids are dilated and congested
Liver centeral lobules show necrosis
Liver cells in periphery shows swelling and fatty degeneration
Has kuffer cell macrophages

Arrow points to kuffer cells

Question 17

Answer 17

Bilharziasis in urinay bladder

Section from urinary bladder wall

Bilharzia ova are deposited on the submucosa. Ova surrouned by bilharzial reaction (lymphocytes, fibrosis, macrophages)
Urothelium shows hyperplasia

yes, can be precancerous

Question 18

Answer 18

Peri-canalicular fibroadenoma

Section in capsulated benign tumor
Proliferated ducts with oval cut in section with patent lumen
Delicate fibrous tissue

Arrow points to duct (non invasive)

Question 19

Answer 19

Intra-canalicular fibroadenoma

section in capsulated benign tumor formed of proliferated ducts (slit like lumen), lined by 2 layer cells
Excess fibrous tissue

Question 20

Answer 20

Infiltrating duct carcinoma

Section in breat showing malignatn tumor formed of infiltrating sheets
Malignant cells are rounded or polygonal variable in shape

shows cellular anaplasia behaviour

Question 21

Answer 21

Infarction in spleen

Section in spleen
Infraction shows structureless pink area. Red and white pulp appear as GHOSTS
3 zones from left to right: infarction, congestion and normal zone

Question 22

Answer 22

Metastatic carcinoma, lymph nodes

In lymph nodes

Partial replacement of nodal tissue by malignant tumor deposits
Tumor is solid in masses

Arrow points to tumor emboli.

Question 23

Answer 23

Caseating TB

In lymphnode
Lymph node is enlarged and partially effaced
Multiple tubercles are seen around caseation

Black arrow is Langerhans giant cell
Red arrow is caseation

Question 24

Answer 24

Lipoma

Section from Benign tumor
Fibrous capsule surrounds tumor creating fibrovascular septa
Lobules are formed of mature fat which are polygonal

arrow points to septa

Question 25

Answer 25

Squamous cell papilloma Branching core of CT showing blood vessels Covered by thick hyperplastic stratified squamous epithelium rarley precancerous Arrow points to core CT

Question 26

Answer 26

Squamous cell carcinoma in Situ section in skin Squamous metaplasia with full thickness and high grade dysplasia Cells show loss of orientation, large. hyperchromatic No invasion of no basement membrane

Question 27

Answer 27

Squamous cell carcinoma Skin Mallignant tumor formed of cell nests formed of outer basal inner polyhedral keratin place. cells show criteria of anaplasia. Inside cell nests is keratin arrow cell nests

Question 28

Answer 28

Fibrosarcoma In malignant tumor SHows proliferated spindle cells Cells have dark elongates nuclei, background is collagenous

Question 29

Answer 29

Actinomycosis section in skin Has many abscesses surrounded by fibrosis Each abscess consists blue fungal colonies surrounded byneutrophils and macrophages Fungal colonies are dark blue Fungal colony

Question 30

Answer 30

Acute suppurative appendicitis Transverse section in appendix Has transmural infiltrate Lumen contains fibrin network entangling necrotic shedded mucosal cell