Patho Slides Flashcards
Myocardial scar
Section in myocardium
Area of scar tissue
Adjacent cardiac muscles are red and slightly atrophic
Arterial thrombus
Transverse section in blood vessels
Lumen is occluded by a thrombus between lines of Zahn which is made of fibrin entangling
Atheroma, small artery
Section in small artery
The empty clefts were occupied by cholesterol
Internal elastic lamina is thinned and so is the media
Thickened subendothelial CT with needle/spindle shaped
Lobular Pneumonia
Section in lung
Alveolar spaces contain network fibrin entangling RBCS and some macrophages
Alveolar wall are thickened and show edema and congestion
Acute nonsuprative fibrinous inflammation
Chronic venous congestion in lung
Lung section
Alveolar wall are thickened due to interstitial edema and congested
Alveolar spaces contain transudate, entangling red cells and hemosiderin granules (the BROWN CELL)
Infarction lung
Lung
The infract show atrophic alveolar wall appears as thin fibrous septa
Rest of lung shows chronic venous congestion
Miliray TB in lung
small tubercles scattered in lung tissue
Each tubercle shows minimal central caseation
Arrow points at giant cells
Acute suppurative appendicitis
The mucosa, submucosa show edema, congested capillaries and exudate
Lumen of the appendix contains fibrin network entangling mucosal cells
Fibrinous peritonitis small intestine
Peritoneum shows shed serosal cell covered by fibrin
Subserosal CT shows edema, congestion and acute infiltrate
Adenoma (intestine)
Benign tumor formed of proliferated acini lined by columnar mucin secreting cells
Some show pseudo-stratification
Vascular CT is found between gland
precancerous
Adenocarcinoma colon
Showing malignant gland
Irregular in shape, and in lumen, lined in anaplasic-like cells
Invading colon
Bilharziasis rectum
section in colonic mucosa
Showing bilharzial granuloma. Many bilharzia ova with reflective shell.
Ova are surrounded by bilharzial reaction (lymphocytes plamsa, fibrosis, giant cells
Non precancerous
Bilharzial polyp
Section in colon
Showing core showing fresh degenerated by bilharzial reaction (lymphocytes, plasma cell, macrophage)
Hyperplastic covering mucosa
Not precancerous
Fibrinous peritonitis
In liver
covering peritoneum shows shedded serosal cells and covered by network fibrin
Has acute inflammatory infiltrate
Subserosal CT shows edema, congested capillary and inflammation
Bilharzial periportal fibrosis
Section in liver
Portal tract is side fibrinous due to bilharzial ova and is surrounded by bilharzial reaction (lymph, plasma cells, macrophage)
Chronic venous congestion of liver
central veins and sinisuoids are dilated and congested
Liver centeral lobules show necrosis
Liver cells in periphery shows swelling and fatty degeneration
Has kuffer cell macrophages
Arrow points to kuffer cells
Bilharziasis in urinay bladder
Section from urinary bladder wall
Bilharzia ova are deposited on the submucosa. Ova surrouned by bilharzial reaction (lymphocytes, fibrosis, macrophages)
Urothelium shows hyperplasia
yes, can be precancerous
Peri-canalicular fibroadenoma
Section in capsulated benign tumor
Proliferated ducts with oval cut in section with patent lumen
Delicate fibrous tissue
Arrow points to duct (non invasive)
Intra-canalicular fibroadenoma
section in capsulated benign tumor formed of proliferated ducts (slit like lumen), lined by 2 layer cells
Excess fibrous tissue
Infiltrating duct carcinoma
Section in breat showing malignatn tumor formed of infiltrating sheets
Malignant cells are rounded or polygonal variable in shape
shows cellular anaplasia behaviour
Infarction in spleen
Section in spleen
Infraction shows structureless pink area. Red and white pulp appear as GHOSTS
3 zones from left to right: infarction, congestion and normal zone
Metastatic carcinoma, lymph nodes
In lymph nodes
Partial replacement of nodal tissue by malignant tumor deposits
Tumor is solid in masses
Arrow points to tumor emboli.
Caseating TB
In lymphnode
Lymph node is enlarged and partially effaced
Multiple tubercles are seen around caseation
Black arrow is Langerhans giant cell
Red arrow is caseation
Lipoma
Section from Benign tumor
Fibrous capsule surrounds tumor creating fibrovascular septa
Lobules are formed of mature fat which are polygonal
arrow points to septa
Squamous cell papilloma
Branching core of CT showing blood vessels
Covered by thick hyperplastic stratified squamous epithelium
rarley precancerous
Arrow points to core CT
Squamous cell carcinoma in Situ
section in skin
Squamous metaplasia with full thickness and high grade dysplasia
Cells show loss of orientation, large. hyperchromatic
No invasion of no basement membrane
Squamous cell carcinoma
Skin
Mallignant tumor formed of cell nests formed of outer basal inner polyhedral keratin place. cells show criteria of anaplasia.
Inside cell nests is keratin
arrow cell nests
Fibrosarcoma
In malignant tumor
SHows proliferated spindle cells
Cells have dark elongates nuclei, background is collagenous
Actinomycosis
section in skin
Has many abscesses surrounded by fibrosis
Each abscess consists blue fungal colonies surrounded byneutrophils and macrophages
Fungal colonies are dark blue
Fungal colony
Acute suppurative appendicitis
Transverse section in appendix
Has transmural infiltrate
Lumen contains fibrin network entangling necrotic shedded mucosal cell
