Pharmacology of anti-inflammatories and immune suppression Flashcards

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1
Q

Rubor=

A

redness

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2
Q

calor=

A

heat

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3
Q

tumor=

A

swelling

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4
Q

dolor=

A

pain

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5
Q

cardinal signs of inflammation (4)

A

redness
heat
swelling
pain

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6
Q

NSAID stands for

A

non steroidal anti-inflammatory

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7
Q

made side effects of NSAIDs related to

A

GI

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8
Q

COX1 inhibitors—>

A

stop formation of platelets

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9
Q

COX2 inhibitors—>

A

anti-inflammatory

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10
Q

2nd generation NSAID called

A

Coxibs

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11
Q

what is different about second generation NSAIDs

A

selective COX-2 inhibitors

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12
Q

what are NO-SAIDs

A

nitric oxide donating NSAID

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13
Q

what is different about NO-SAIDs

A

have GI protective effect and increased anti-inflammation

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14
Q

SAID=

A

Glucocorticoids

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15
Q

e.g of SAIDs (2)

A

Hydrocortisone

prednisolone

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16
Q

what do glucocorticoids do

A

decrease IL-2, IL-3, IL-4, TNF alpha

17
Q

side effect of glucocorticoids

A

cushing’s syndrome

18
Q

name 2 immunosuppresant drugs

A

cyclosporine

tacrolimus

19
Q

what is the most important effect of immunosuppression drugs

A

IL-2 gene reduction