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d.b.review 2 > Pharmacology II > Flashcards

Pharmacology II Flashcards

1
Q

Drugs with slight anticholinergic effects

A

DiTriBeAM

diophenhydramine
Tricyclic antidepressants
Benzodiazepines
Antipsychotics
Meperidine
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2
Q

Gold standard of narcotics

A

Morphine

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3
Q

Narcotics aka

A

Opioids
Opiates
Opium

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4
Q

Morphine came from what plant

A

Poppy plant

Papaver somniferum

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5
Q

Opioid receptors (4)

A

Limbic system
Area postrema
Solitary nuclei
Substansia gelatinosa of rolando

LASS

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6
Q

Most common side effect of narcotics

A

Nausea

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7
Q

Gate in gate control theory

A

Substansia gelatinosa of rolando

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8
Q

Most accepted theory for pain

A

Gate control theory

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9
Q

Opioid receptor responsible for nausea and vomiting

A

Area postrema

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10
Q

Anti tussive drug

A

Dextromethorpan (rubitussin)

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11
Q

Opioid receptor responsible for gag reflex cough reflex baroreceptor reflex chemoreceptor and gastric motility

A

Solitary nuclei

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12
Q

Endogenous opioids produced by body (2)

A

Enhephalins

Endorphins

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13
Q

Combination of Diphenoxylate and Atropine

A

Lomotic

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14
Q

Laxative drug

A

Bisacodyl

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15
Q

Drug for expectorant

A

Guaifenesin

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16
Q

Narcotic agents block pain in PNS T or F

A

False

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17
Q

Morphine triad

A

Miosis
Respi depression
Coma

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18
Q

Components or drugs of neuroleptic analgesia

A

Neuroleptic agents or antipsychotics
Narcotics
Nitrous oxide

3N

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19
Q

example of neuroleptic drug

A

butyrophenones

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20
Q

Drug that causes dissociative anesth

A

Ketamine

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21
Q

*drug that places px in trans like state

A

Ketamine

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22
Q

Contraindicated drugs to glaucoma

A

Diazepam
Anticholinergic drugs!!!
(ditribeam)

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23
Q

Other name of heroin

A

Diacetylmorphine

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24
Q

Other name for acetaminophen

A

APAP

N-acetyl paraminophenol

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25
Q

Oxycodone + acetaminophen = ______

A

Tylox

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26
Q

Drug for orofacial pain

A

Codeine

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27
Q

Real anticholinergics ***

A

Belladona alkaloids
Atropine
Scopolamine

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28
Q

Dse Associated with px taking meth

A

Meth mouth

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29
Q

drug that shouldnt be combined with MAO inhibitors

A

MEPERIDINE

SSRI
Ephedrine
Epineph

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30
Q

Street name for heroin

A

Horse
Big H
Brown sugar

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31
Q

Street name for cocaine

A

Coke

Candy

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32
Q

Street name for methamphetamine HCL

A

Crystals
Meth
Shabu
Poorman’s cocaine

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33
Q

Street name for marijuana

A

MJ
Weed
Blunt

Came from cannabis sativa

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34
Q

Oxycodone drug

A

Percocet

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35
Q

Route of administration

Codeine, oxycodone, methadone

A

Oral

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36
Q

Morphine and meperidine route of administration

A

Parenteral (IV)

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37
Q

Narcotic antagonists (2)

A

Naloxone

Naltrexone

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38
Q

Drugs with respiratory depression and dependence (4)

A

SNAB

Sedative hypnotics
Narcotics
Alcohol
Benzodiazepines

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39
Q

Impaired control over taking the drug

A

Psychic dependence

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40
Q

Continued administration of the drug is required to prevent unpleasant withdrawal syndrome

A

Physical dependence

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41
Q

Inhalation drugs

A

Halothane

Desflurane

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42
Q

Blocks cox in CNS

A

Acetaminophen

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43
Q

Acetaminophen is ____ acting

A

Centrally acting non narcotic analgesic

44
Q

Hepatotoxic drugs

A

Acetaminophen
Rifampicin
Tetracyclines

45
Q

Narcotics metabolized to a CNS stimulant

A

Meperidine (Demerol) - NORmep

Propoxyphene (Darvon)

46
Q

Drugs with different classification from books opioids or non opioids

A

Tramadol
Propoxyphene (Darvon)
Petazocaine (Talwin)

47
Q

Non scheduled narcotics

A

Tramadol

48
Q

Drugs with neuroleptic anesthesia (3)

A

Narcotic
Butyrophenones (anti psychotic)
Nitrous oxide

49
Q

Receptor of leukotrienes

A

Leukotriene receptor

50
Q

If leukotrienes binds to receptor it will result to ______

A

Bronchoconstriction - reason for asthma

51
Q

Prevent bronchoconstriction of leukotrienes

A

Leukotriene receptor blocker

52
Q

Leukotriene receptor blocker drug

A

Montelukast

53
Q

Both CNS and PNS have cyclooxygenase T or F

A

True

54
Q

If arachidonic acid went to CNS there would be production of ____

A

CoX2 - produces prostaglandins

55
Q

Effect of prostaglandin to CNS

A

Fever

Pain

56
Q

Cox 1 in PNS produces

A

Thromboxane A2 - formed by platelets

Prostaglandins

57
Q

Prostaglandin in cox 1 PNS effect

A

Inc renal blood flow

58
Q

Cox 2 in PNS produces

A

Prostaglandins

Prostacyclin

59
Q

Effects of prostaglandin in cox 2 PNS

A

Pain

Vasodilation

60
Q

Effect of prostacyclin in cox 2 PNS

A

Vasodilation

61
Q

3 end product of cyclooxygenase

A

Prostaglandin
Prostacyclin
Thromboxane a2

62
Q

Non narcotics takes place to PNS except what drug

A

Acetaminophen

63
Q

Drug that inhibit both COX 1 and 2 and is mainly peripherally acting

A

nsaids

64
Q

Uses of non narcotic agents (3)

A

Anti pyretic
Analgesic
No inflam effect

65
Q

Aspirin irreversibly block ____

A

Cox 1 in platelets

66
Q

Aspirin and salicylates PNS or CNS

A

PNS

67
Q

Prior to surgery, when should px stop taking aspirin

A

7 days

68
Q

Reye’s syndrome

A

Child
Viral
Aspirin

69
Q

Drug used to treat salicylism

A

Sodium bicarbonate

70
Q

What parent drug is converted to acetaminophen

A

Phenacetin

71
Q

Narcotic agents when excessive dose can lead to narcotic like adverse effects (2)

A

Pentazocaine

Propoxyphene

72
Q

Aspirin + NSAIDS can enhance (2)

A

Warfarin (Coumadin)

Coumarin

73
Q

NSAIDS drug uses (3)

A

Anti inflam
Analgesics
Mild anti pyretic

74
Q

Which of the ffg drug should not be given if px will undergo surgery

A

NSAIDS (aspirin) PART OF NSAIDS PADIN

75
Q

NSAID that selectively blocks COX 2

A

Cox 2 inhibitor

76
Q

Only nsaid with no side effects

A

Cox 2 inhibitors

77
Q

Type of non narcotic without anti inflam effect

A

Acetaminophen

78
Q

Classification of aspirin (3)

A

Non narcotic
NSAID
salicylates

79
Q

Drg uses of aspirin (4)

A

Anti pyretic
Analgesics
Mild anti inflam
Blood thinner

80
Q

Overdose of aspirin

A

Salicylism

81
Q

Cox 2 inhibitor drugs

A

Celecoxib
Etoricoxib
Valdecoxib

82
Q

Ideal days for taking cox 2 inhibitor

A

7days

83
Q

Cox 2 inhibitors reduces pain, fever, and inflammation without having GI problems T or F

A

True

84
Q

Steroidal drugs suffix

A
  • sone

- lone

85
Q

Corticosteroids rx

A

Bilateral mandibular radiolucencies

86
Q

Steroidal drugs inhibits ____ resulting to dec arachidonic acid

A

Phospholipase a2

87
Q

Steroidal drug uses

A 
Anti inflam
Immunosuppressants
Prevents graft rejection
Prevents prosthetic rejection
Tx for addison dse
88
Q

*before surgical extraction, what will do if px is under long term steroidal therapy

A

Increase dose or double the dose

89
Q

Antipsychotic drugs aka (3)

A

Major tranquilizers
Neuroleptic agents
Hallucinogens

90
Q

Dse with excessive dopamine levels

A

Schizophrenia

91
Q

Dse with dec dopamine

A

Parkinson’s dse

92
Q

Adverse effect of first gen antipsychotics

A

Extra pyramidal syndrome (tardive dyskinesia)

93
Q

First gen antipsychotic drugs (3)

A

Phenothiazines - chlorpromazine
Butyrophenones - droperidol
Thioxanthenes

94
Q

Second gen antipsychotic drug

A

Clozapine

95
Q

Second gen has (4) receptor antagonist in limbic system

A

D1
D2
D4
D5

96
Q

Bipolar disorder aka

A

Manic depression syndrome

97
Q

DOC for manic depressive syndrome

A

Lithium ion

98
Q

Antidepressant drug given to bipolar px

A

Tricyclic antidepressants

99
Q

Most common TCA

A

Amitriptyline (si ami laging pinagttripan)

100
Q

Drug given to px with tourettes

A

Antipsychotic drugs

101
Q

Pharma effects of antipsychotics (5)

A 
Reduction in psychosis
Emotion quieting
Dec convulsion
Sedation
Anticholinergic effect
102
Q

Adverse effect of antipsych drugs

A

Tardive dyskinesia
Parkinsonism
Akathisia

103
Q

Antipsychotic mainly d2 receptor antagonist

A

First gen antipsychotics

104
Q

Antipsychotic drug with antihypertensive properties

A

Reserpine

105
Q

Drugs for parkinsons dse (4)

A

L-dopa
Stimulants
MAO inhibitors
Anticholinergic drugs

106
Q

Neuroleptic analgesia
A. Narcotics
B. Butyrophenones
C. N2O2

A

C

107
Q

Which of the ffg drugs can be used to treat parkinsonism like symptoms
A. Anticholinergic
B. Narcotics
C. Antidepressants

A

A.

d.b.review 2 (21 decks)

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