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d.b.review 2 > Antibiotics > Flashcards

Antibiotics Flashcards

1
Q

Drugs that kill or inhibit the growth of microorganism

A

Antibiotics

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2
Q

Inhibit bacterial growth and multiplication

A

Bacteriostatic

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3
Q

Kills bacteria

Inhibit formation of _____ during cell division

A

Bacteriocidal

Cell wall

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4
Q

What part of bacterial does bacteriostatic take effect

A

Exponential phase

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5
Q

Can bacteriostatic and bactericidal be combined?

A

No

They are antagonists

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6
Q

All cell wall synthesis inhibitors are cidal or static

A

Barteriocidal

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7
Q

Cell wall synthesis inhibitor drugs (4)

A

PCMC - beta lactam rings
Glycopeptides - Vancomycyn
Bacitracin - topical antibiotic
Cycloserine - for TB

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8
Q

Beta lactam drugs

A

PCMC

Penicillin
Cephalosporins
Monobactams
Carbepenems

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9
Q

Tx for pseudomembranous colitis

A

Vancomycin

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10
Q

Pseudomembranous colitis is associated with what drug

How to treat

A

Clindamycin

Vancomycin
Metronidazole

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11
Q

Tx for MRSA or methicillin resistant staph aureus

A

Vancomycin

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12
Q

Used drugs if there’s infection gram + strep or staph (4)

A

Penicillin
Erythromycin
Cephalosporins

PEC

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13
Q

Antibiotics for oral infections has min of ___ days

A

5 days

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14
Q

Enzyme against penicillin

A

Penicillinase aka beta lactamase!! Since. Ay beta lactam rings ang penicillin

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15
Q

Resistant to penicillins aka

A

Penicillin resistant staph aureus (PRSA)

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16
Q

Type of penicillins classified as penicillinase resistant penicillins

A

Methicillin

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17
Q

Methicillin resistant aka

A

Methicillin resistant staph aureus (MRSA)

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18
Q

Drug for MRSA

A

Vancomycin (IV)

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19
Q

Last resort to antibiotics

A

Colistin

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20
Q

Protein synthesis inhibitor drugs (6)

A

AT30MCC50S

Aminoglycosides
Tetracycline fam
Macrolides
Clindamycin
Chloramphenicol

Lincomycin

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21
Q

Only bactericidal protein synthesis inhibitory drug

A

Aminoglycosides

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22
Q

Blocks 30s with very broad spectrum or BROADEST SPECTRUM *

A

Tetracycline family

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23
Q

Aminoglycosides drugs (4)

A

Streptomycin
Gentamicin
Tobramycin
Neomycin

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24
Q

Tetracycline drugs (3)

A

TetraCYLCINE
DoxyCYLCINE
MinoCYCLINE

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25
Adverse effect of aminoglycosides
Ototoxicity
26
Adverse effect of tetracyclines
Hepatotoxic Photosensitivity Resistant and superinfections Tooth discoloration
27
Drugs common with photosensitivity (3)***
Tetracycline Ibuprofen Naproxen
28
Macrolides drugs (3)
MACE Azithromycin Clarithromycin Erythromycin
29
First macrolide with most severe side effect
Erythromycin
30
Blocks 50s ribosomal unit used when allergic to penicillin
Clindamycin
31
Blocks 50s ribosomal unit use as last resort due to high toxicity and adverse effect
Chloramphenicol
32
AE of chloramphenicol (2)
Gray baby syndrome | Hemolytic anemia
33
If dose is increased in clindamycin it will be converted into ____
Bactericidal effect
34
Biosynthetic pathway inhibitor drugs (3)
Trimethoprim Sulfonamides Fluroquinolones
35
Sulfa drugs that mimics PABA
Sulfonamides
36
Sulfonamides static or cidal
Static - mimic paba
37
Co trimoxazole (Bactrium) is a combination of what drugs
Trimethoprim | Sulfamethoxazole
38
Brand of co trimoxazole
Bactrim
39
Quinolones are derived from
Quinine
40
Quinidine is used for
Anti arrhythmic
41
Causes the antimicrobial property of penicillins
Beta lactam rings
42
Penicillins from fungi | Types (2)
Natural penicillins Pen G Pen VK
43
First penicillin produced
Pen G - IV | Benzylpenicillin
44
Pen VK aka
Phenoxybemethyl penicillin - oral
45
Penicillin from narrow to a little broad spectrum | But classified as BROAD SPECTRUM
Extended penicillins
46
Type of extended penicillins
Aminopenicillins - Amoxicillin - ampicillin
47
Most commonly used when giving oral prophylactic antibiotics
Amoxicillin
48
Dosage of amox and ampicillin prior to invasive procedure
2 g or 2000 mg | 30-60 mins
49
Dosage of amox to children
50 mg/kg
50
Given if oral route is not available alternative for amox
Ampicillin (parenteral)
51
Has the widest spectrum of all penicillins aka
Broad spectrum penicillin | Antipseudomonas penicillins
52
Broad spectrum penicillin drug (2)
Piperacillin | Ticarcillin
53
Dosage of clindamycin in adult and kids
20 mg /kg 600 mg Oral/IM/IV
54
Penicillinase resistant penicillins aka
Antistaphylococcal penicillins
55
Drugs resistant to penicillinase (5)
``` Methicillin Nafcillin Cloxacillin Oxacillin Dicloxacillin ```
56
Major disadvantage of broad antibiotics (2)
Resistance | Superinfections
57
Co amoxiclav (Augmentin) is a combination of
Amoxicillin | Clavulanic acid
58
Clavulanic acid has ____ inhibitor
Beta lactamase
59
Has cross allergenicity to penicillins
Cephalosporins
60
doc for upper respiratory tract infections
Co amoxiclav
61
Broad spectrum antibiotics with four generations Has disulfiram With beta lactam rings
Cephalosporins
62
With low cross allergenicity to penicillins
Monobactams
63
Drugs with slight resistance to penicillinase (3)
Cephalosporins Monobactams Carbapenemes
64
Topical antibiotics (3)
Bacitracin Polymyxin B Neomycin
65
Antifungal Drugs administered parenteral
Amphotericin B
66
Most potent antifungal drug
Griseofulvin

d.b.review 2 (21 decks)

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