Pharmacology Exam 1 Flashcards
Pharmacology
the study of drugs
Drug
any chemical that effects the physiological process of a living organism
Prescription Medications
legend drugs (approved by FDA)
need prescription
Over the counter (OTC) medications
Account for 60% of all drugs used
do not need prescription
Dietary Supplements
Herbals
Vitamins
Minerals
Illegal Drugs
Marijuana
Cocaine
Heroin
FDA
Food and Drug Administration
High therapeutic index
pretty safe
Black Box Warnings
serious risk of taking drug
DEA
Drug Enforcement Agency
*enforce controlled sustances laws and regulation of the U.S.
Schedule I
Highest potential for abuse
*No accepted medical use in the US
Schedule II
High potential for abuse
*legal in US (accepted medical use)
Schedule III
Lower potential for abuse than I & II
(Combination drugs)
Schedule IV
Low potential for abuse
(Anti-Anxiety)
Schedule V
Lowest potential for abuse
(Cough/pain)
Drug Diversion
transfer of any legally prescribed controlled substance from the individual for whom it was prescribed to another person for illicit use.
Pharmacokinetics
the branch of pharmacology concerned with the movement of drugs within the body.
-absorption
-distribution
-metabolism
-elimination
Factors that impact absorption
Common routes of Med Administration & Considerations
First Pass Effect
the metabolism of a drug and its passage from the liver into the circulation
(oral drugs)
Bioavailability
the extent of drug absorption into systemic circulation
Lifespan Considerations
-age
-weight
Factors that Impact Distribution
Protein binding
Blood brain barrier
Half life
Factors that Impact Metabolism
Factors that Impact Excretion
Routes of Excretion
Pharmacodynamics
the branch of pharmacology concerned with the effects of drugs and the mechanism of their action.
Drug/Receptor Interaction
Agonist
Antagonist
Prescription Medications
OTC Medications