Pharmacology: Antimicrobials Flashcards

1
Q

Penicillin G

A

IV penicillin, beta-lactam

  1. Binds PBP
  2. Blocks transpeptidase cross-linking of peptidoglycan
  3. Activate autolytic enzymes
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2
Q

Penicillin V

A

PO penicillin

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3
Q

Methicillin

A

Penicillinase-resistant penicillin

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4
Q

Nafcillin

A

Penicillinase-resistant penicillin

Naf for Staph!

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5
Q

Dicloxacillin

A

Penicillinase-resistant penicillin

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6
Q

Ampicillin

A

Wider spectrum beta-lactam, penicillinase-sensitive

HELPSS kill Enterococci

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7
Q

Amoxicillin

A

Wider spectrum beta-lactam, penicillinase-sensitive

HELPSS kill Enterococci

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8
Q

Ticarcillin

A

Extended-specturm beta-lactam (same as PCN)
Penicillinase-sensitive, use with beta-lactamase inhibitor
Covers Pseudomonas! And GNRs!

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9
Q

Carbenicillin

A

Extended-specturm beta-lactam (same as PCN)
Penicillinase-sensitive, use with beta-lactamase inhibitor
Covers Pseudomonas! And GNRs!

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10
Q

Piperacillin

A

Extended-specturm beta-lactam (same as PCN)
Penicillinase-sensitive, use with beta-lactamase inhibitor
Covers Pseudomonas! And GNRs!

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11
Q

Clabulanic acid

A

Beta-lactamase inhibitor

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12
Q

Sulbactam

A

Beta-lactamase inhibitor

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13
Q

Tazobactam

A

Beta-lactamase inhibitor

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