Pharmacology: Antimicrobials Flashcards
Penicillin G
IV penicillin, beta-lactam
- Binds PBP
- Blocks transpeptidase cross-linking of peptidoglycan
- Activate autolytic enzymes
Penicillin V
PO penicillin
Methicillin
Penicillinase-resistant penicillin
Nafcillin
Penicillinase-resistant penicillin
Naf for Staph!
Dicloxacillin
Penicillinase-resistant penicillin
Ampicillin
Wider spectrum beta-lactam, penicillinase-sensitive
HELPSS kill Enterococci
Amoxicillin
Wider spectrum beta-lactam, penicillinase-sensitive
HELPSS kill Enterococci
Ticarcillin
Extended-specturm beta-lactam (same as PCN)
Penicillinase-sensitive, use with beta-lactamase inhibitor
Covers Pseudomonas! And GNRs!
Carbenicillin
Extended-specturm beta-lactam (same as PCN)
Penicillinase-sensitive, use with beta-lactamase inhibitor
Covers Pseudomonas! And GNRs!
Piperacillin
Extended-specturm beta-lactam (same as PCN)
Penicillinase-sensitive, use with beta-lactamase inhibitor
Covers Pseudomonas! And GNRs!
Clabulanic acid
Beta-lactamase inhibitor
Sulbactam
Beta-lactamase inhibitor
Tazobactam
Beta-lactamase inhibitor