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MSK 1 > Pharmacology And Thereapeutics - Treatment Of Pain : Simple Analgesics And Opiods > Flashcards

Pharmacology And Thereapeutics - Treatment Of Pain : Simple Analgesics And Opiods Flashcards

1
Q

A patient presents with muscle pain after being in a fight. What type of pain would this be classified as ?

A. Nociceptive pain
B.nociceptive somatic pain
C.nocicpetive visceral pain
D.neuropathic pain

A

B.nociceptive somatic pain

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2
Q

A baby presents with consistent and long lasting crying what type of pain would be the likely cause behind this ?

A.nocicpetive visceral
B.nocicpetive visceral
C.neuropathic

A

B.nociceptive visceral (colic)

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3
Q

A a patient is prescribed opioids for pain management. At what point of the pain ladder are opioids introduced ?

A.stage 1
B.stage 2
C. Stage 3
D.stage 4

A

B.stage 2

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4
Q

A patient presents with moderate to mild pain and is given opioids in combination with a non opioid and an adjuvant what stage of the pain ladder would this patient be placed at ?

A.stage 1
B.stage 2
C.stage 3
D.stage 4

A

B.stage 2

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5
Q

A patient presents with moderate to severe pain pain what step of the pain ladder would they be placed on and what treatment would be most likely ?

A. Step 3 - opioids
B.step 4 - adjuvant
C.step 1-opioids

A

A.Step 3 -opioids

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6
Q

A patient takes paracetamol and NSAIDs What form of pain management drugs are these ?

A.simple analgesics 
B.pain killers 
C. Opioid agonists 
D.opioid anatagonists 
E. Strong opiod agonists
A

A.simple analgesics

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7
Q

A patient is prescribed an opioid against from what group of drugs would a suitable prescription be made ?

A. Paracetamol, codeine, morphine

B.paracetamol, codeine, dihydroxodeine

C. Codeine, dihydrocodeine, morphine

D.codeine, dihydrocodeine, tramadol

A

D. Codeine dihydrocodeine and tramadol are all opioids

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8
Q

A patient presents with severe pain what drug would be most suitable ?

A.NSAIDs
B. Dihydrocodeine
C.morphine
D. Tramadol

A

C. Morphine

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9
Q

Patient presents with moderate pain what drug would be most appropriate to administer ?

A.paracetamol 
B. Codeine 
C.diamorphone
D.ibruprofen
C.morphine
A

B.codeine

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10
Q

Patient prescribed paracetamol for pain. What best describes the action of paracetamol ?

A. Anti inflammatory
B. Inhibits prostaglandin sysnthesus via CNS inhibition of cox3 peripherally blocks generation of pain impulses
C. Inhibits prostoglandin synthesis via inhibiting dopamine breakdown
D. Work at the MU receptor to reduce synaptic transmission of pain

A

B. B. Inhibits prostaglandin sysnthesus via CNS inhibition of cox3 peripherally blocks generation of pain impulses

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11
Q

Patient presents with mild to moderate pain without inflammation which drug is most suitable ?

A.brufin
B.paracetamol
C.NSAIDS
D.tramadol

A

B.paracetamol

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12
Q

Patient administered paracetamol. What are possible contraindications for paracetamol use?

A.bleeding
C.old age and liver impairment
D.low body weight and liver impairment

A

D.low body weight and liver impairment

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13
Q

Patient suffers liver damage following high does or paracetamol. In order to breakdown paracetamol and avoid hepatic and renal damage what antioxidant is required ?

A.anti A
B. Gultathione
C.glutamine
D.mercapturic acid

A

B.glutathione

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14
Q

In paracetamol overdose what intermediate BRoken down by glutathione is responsible for renal and hepatic damage

A.N acetyl cysteine
B. n acetyl p benzoquinonimine
C.5- oxoproline

A

B.N acetyl p benzoquinonimine

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15
Q

Patient overdosed on paracetamol. What drug is used to neutralise the intermediate metabolite produced?

A. Oxoproline
B.glutathione
C. Vitamin k
D. N acetyl cysteine

A

D. n acetyl cysteine

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16
Q

A patient on flucloxacillin should take precautions when taking which painkiller ?

A.ibruprofen
B.paracetamol
C. Morphine
D.tramadol

A

B.paracetamol

17
Q

A patient taking an pain killing drug complains of an itchy nose, constipation ,nausea , decreasing respiratory rate and drowsiness. On investigation they have pupillary constriction. What form of painkiller is likely to be responsible ?

A.opioid
B.NSAIDs
C. Paracetamol
D.analgesic

A

A.opiod

18
Q

A patient in severe pain after a fall is prescribed opioids. What best described the mechanism of action of opiod a?

A. Inhibit prostaglandin sysnthesis via cns inhibition or cox3 peripherally blocking pain generation

B.acts on Mu receptor in post and presynaptic neurons to have downstream effects reducing calcium entrance to the neutron and release of substance p and acts on post synaptic k+ channel to reduce the resting potential and stop AP generation

A

B B.acts on Mu receptor in post and presynaptic neurons to have downstream effects reducing calcium entrance to the neutron and release of substance p and acts on post synaptic k+ channel to reduce the resting potential and stop AP generation

19
Q

Opiods are prescribed for servere pain what receptor do opiods work on the most ?

  1. Delta
  2. kappa
  3. Mu
A

3.Mu

20
Q

Patient elderly and taking SSRIs what drug should be avoided for moderate to servere pain due to contraindications ?

A.codeine
B.morphine
C.paracetamol
D. Tramadol

A

D.tramadol

21
Q

A patient is in severe pain and has no past drug history of opiods. What formulation of opiod should be given ?

A.short acting
B.long acting
C. Pethidine

A

A.short acting

22
Q

Patient on a long course of long acting opiods experiencing breakthrough pain what should be administered ?

A.short acting, same opiod
B. Long acting, different opiod
C. Short acting, different opiod

A

A.short acting, same opiod

23
Q

A patient is experiencing breakthrough pain despite being on long acting morphine. What other opiod should be administered ?

A. Short acting, tramadol 1/6th daily dose
B. Short acting, dihydromorphine 1/4th daily does
C. Short acting morphine 1/6th daily dose
D.paracetamol

A

C.short acting morphine always 1/6th dialog does

24
Q

Which of these patients would it be safe to administer opiods for pain to ?

A. Girl, impaired pulmonary function 
B. Boy impaired renal function 
C. Elderly man 
D. Middle aged woman awaiting x ray for broken bones 
E. Girl with hypothyroidism 
F. Patient with concussion
A

D. Middle aged woman awaiting z ray for broken bones

25
Q

A patient is given a constant dose of opiods for back pain. However over time they have noticed a decreased effect from the drug . What term best describes this phenomena ?

A. Addiction
B. Relapse
C. Tolerance
D.adaptation

A

C.tolerance

26
Q

When switching a patient from one opiod to another how much should a dose be reduced by in order to avoid issues with cross tolerance ?

A.50% 
B.25%
C.25-55%
D.25-50%
E.30-60%
A

D. 25 -50 %

27
Q

A patient suddenly stops taking their prescribed pain killer and experiences withdrawal symptoms including: diarrhoea, restlessness and hyperventilation what painkiller type were they like to be taking ?

A.analgesic
B.opiod
C.analgesic

A

B.opiod

28
Q

A patient has overdosed on opiods and Naloxone is administered to reverse this. What type of drug is naloxone ?

A.competitive antagonist
B.competitive agonist
C.irreversible inhibitor
D. Reversible antagonist

A

A.competitive antagonist

MSK 1 (23 decks)

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