pharmacology and therapeutics 12

Question 1

Explain the mechanisms of regulating vascular tone and total peripheral resistance

Question 2

Define hypertension, and what is it a major risk factor of, and the goal of hypertension therapy

Question 3

Explain what happens in the renin-angiotensin system, and explain how ACE inhibitors are used in heart failure , hypertension and diabetic nephropathy

Question 4

Explain how angiotensin receptor blockers a are used and give their side effect(also side effect of ACEi, but more to do with ARB)

Question 5

Explain the use of calcium channel receptor blockers as an antihypertensive

Question 6

Explain use of alpha blockers as antihypertensives

Question 7

Describe the steps of drug treatment in hypertension, with reasons why there are two possible steps for initial treatment

Question 8

How effective are RASi compared to CCBs , thiazide and beta-blockers for treating HF, stroke snd hypertension and where relevant CV events.