Pharmacology Flashcards

1
Q

Name some Dihydropyridines

A

Nifedipine

Amlodipine

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2
Q

What do dihydropyridines do

A

Affect vascular smooth muscle

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3
Q

Name some phenylalklyamines

A

Verapimil

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4
Q

What do phenylalkylamines do?

A

Negatively chronotrophic and ionotrophic

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5
Q

What are 3 types of CCBs

A

Dihydropyridines
Phenylalklyamines
Benzothiazepines

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6
Q

Name some benzothiazepines

A

Diltiazem

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7
Q

What does diltiazem do?

A

Heart and peripheral vascular effects

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8
Q

What are side effects of vascular acting CCBs

A
Flushing
Headache
Oedema
Palpitations
Nifedipine causes reflex tachy and headaches
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9
Q

What are side effects of central acting CCBs?

A
Brady (reduced CO)
AV block
Can worsen heart failure
Not used with BBs
Constipation
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10
Q

Name some B1 selective BBs

A

Bisoprolol

Misoprolol

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11
Q

What do B1 BBs do?

A

Cardioselective

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12
Q

Name some non selective BBs

A

Propanolol

Atenolol

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13
Q

What are side effects of BBs?

A

Fatigue
Headache
Brady
Raynauds and claudication worsened

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14
Q

Name a thiazide diuretic

A

Bendroflumethiazide

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15
Q

Name 2 loop diuretics

A

Furosemide

Bumetanide

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16
Q

Name 2 K sparing diuretics

A

Spironolactone

Amiloride

17
Q

What are side effects of loop diuretics?

A

Hypovolaemia

Hypotension

18
Q

What are side effects of Thiazide diuretics

A

Gout

Erectile dysfunction

19
Q

What are side effects of all diuretics?

A

Hyponatremia
Hypokalaemia
HYpomagnesia
Hypocalcaemia

20
Q

Name a nitrate

A

Isosorbide mononitrate

21
Q

How do Nitrates work?

A

Vasodilate arteries and veins reducing preload and afterload lowering BP`

22
Q

When are thiazides contraindicated?

A

Gout

Hypercalcaemia

23
Q

When are BBs contraindicated?

A

Asthma
Unstable heart failure
Heart block
Verapimil

24
Q

When are ACEi contraindicated?

A

Renal artery stenosis
NSAIDs
K sparing diuretics
Pregnancy

25
Q

What are side effects of ACEi

A
Angioedema
First dose hypotension
Renal failure
Hyperkalaemia
Bradykinin cough
Rash