Pharmacology Flashcards

1
Q

Paracetamol OD

A

> 150mg/kg (75mg/kg if malnourished) or 12g
Vomiting RUQ pain: later encephalopathy, jaundice, liver/renal failure
Activated charcoal 8h just start NAC
Monitor INR, LFT, U+E, hourly BM

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2
Q

Steroid long term:

Extras

A
Gastric protection (PPI) 
Bone protection (alendronate )
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3
Q

Steroids long term:

Side effects

A
Osteoporosis
Weight gain
Immunosuppression
HTN
Skin thinning 
Stomach ulcer
Cataracts
Mood
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4
Q

Adenosine:

Contraindication

A

Asthma

Long QT

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5
Q

Verapamil:

Drug interaction contraindication

A

Beta blockers

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6
Q

Ca channel blockers:

Side effects

A

Headache

Ankle swelling

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7
Q

Thiazides:

Side effect

A

Hypercalcaemia
Gout
Worsens digoxin toxicity

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8
Q

ARBs:

Side effects

A

Hyperkalaemia

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9
Q

Amiodarone:

Side effects

A

Hypothyroidism

Interstitial lung disease

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10
Q

Verapamil:

Side effects

A

Heart block

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11
Q

Amiodarone:

Contraindications

A

Preg/ breastfeeding

Heart block

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12
Q

Sulfalazine:

Side effects

A

Myelosuppression
Oligospermia
Hepatitis

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13
Q

Gold:

Side effects

A

Nephrotic syndrome

Marrow suppression

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14
Q

Penicillamine:

Side effects

A

Taste disturbance
Nephrotic syndrome
myasthenia

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15
Q

Chloroquine:

Side effects

A

Retinopathy

Tinnitus

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16
Q

Salicylate OD

A

haemodialysis

17
Q

Opiate OD

A

Naloxone

18
Q

Benzo OD

A

Flumenazil

19
Q

Heparin OD

A

Protamine