Pharmacology Flashcards
Paracetamol OD
> 150mg/kg (75mg/kg if malnourished) or 12g
Vomiting RUQ pain: later encephalopathy, jaundice, liver/renal failure
Activated charcoal 8h just start NAC
Monitor INR, LFT, U+E, hourly BM
Steroid long term:
Extras
Gastric protection (PPI) Bone protection (alendronate )
Steroids long term:
Side effects
Osteoporosis Weight gain Immunosuppression HTN Skin thinning Stomach ulcer Cataracts Mood
Adenosine:
Contraindication
Asthma
Long QT
Verapamil:
Drug interaction contraindication
Beta blockers
Ca channel blockers:
Side effects
Headache
Ankle swelling
Thiazides:
Side effect
Hypercalcaemia
Gout
Worsens digoxin toxicity
ARBs:
Side effects
Hyperkalaemia
Amiodarone:
Side effects
Hypothyroidism
Interstitial lung disease
Verapamil:
Side effects
Heart block
Amiodarone:
Contraindications
Preg/ breastfeeding
Heart block
Sulfalazine:
Side effects
Myelosuppression
Oligospermia
Hepatitis
Gold:
Side effects
Nephrotic syndrome
Marrow suppression
Penicillamine:
Side effects
Taste disturbance
Nephrotic syndrome
myasthenia
Chloroquine:
Side effects
Retinopathy
Tinnitus