Pharmacology Flashcards
receptor binding
FA 242
G-protein-linked 2nd messengers
FA 244
Cholinesterase inhibitor poisoning
Often due to organophosphates, such as parathion, that irreversibly inhibit AChE. (DUMBBELSS) Causes Diarrhea, Urination, Miosis, Bronchospasm, Bradycardia, Excitation of skeletal muslce and CNS, Lacrimation, Sweating, and Salivation. Tx - atropine (competitve inhibitor) + pralidoxime (regenerates AChE if given early)
Atropine toxicity
“Hot as a hare, Dry as a bone, Red as a beet, Blind as a bat, Mad as a hatter” inc body temperature (due to dec sweating); rapid pulse; dry mouth; dry, flushed skin; cycloplegia; constipation; disorientation.
alpha blockers
FA 250
beta blockers
FA 251
Drug reactions
252-255
Drug names
FA 256