Pharmacology 2

Question 1

function of digoxin

Answer 1

regulates calcium influx into heart increasing force of contractions but slowing down contractions

Question 2

ADR’s of digoxin

Answer 2

dysrhythmias, headaches, fatigue, malaise, confusion, low K+ levels

Question 3

function of antidysrhythmias/antiarrhythmics

Answer 3

drugs used to prevent or correct a cardiac arrhythmia

Question 4

function of adenosine (unclassified)

Answer 4

slows conduction through AV node

Question 5

what are the classes of vaughan williams classification

Answer 5

class l- Na+ channel blockers
class ll- B-blockers
class lll- K+ channel blockers
class lV- Ca+ channel blockers

Question 6

examples of class l Na+ blockers

Answer 6

procainamide, quinidine, lidocaine, flecainide, propafenone

Question 7

examples of class ll B-blockers

Answer 7

anything ending in olol or lol

Question 8

examples of class lll K+ blockers

Answer 8

amiodarone, dronedarone (darone)

Question 9

ADR’s of class lll K+ blockers

Answer 9

skin can turn blue/purple, pulmonary toxicity, can affect nearly every organ

Question 10

examples of non-dihydropyridine CCB’s class lV

Answer 10

verapamil, diltiazem

Question 11

hemostasis vs bleeding

Answer 11

hemostasis

term for process that stops bleeding

Question 12

what is a thrombus

Answer 12

a blood clot

Question 13

what is an embolus

Answer 13

a blood clot that moves through the blood vessels

Question 14

what is the result of coagulation

Answer 14

fibrin, a clot forming substance that holds platelets together and stops blood flow

Question 15

what is the intrinsic pathway

Answer 15

• activated by internal trauma
• factors Vlll, lX, Xl, and Xll
• slow

Question 16

what is the extrinsic pathway

Answer 16

• activated by external trauma
• factor Vll
• fast

Question 17

what is the function of heparins (anticoagulants)

Answer 17

inhibits clotting factors lla, Xa, and lX

Question 18

what is the function of anticoagulants

Answer 18

decreases blood coagulation (also known as blood thinners)

Question 19

examples of heparins

Answer 19

anything ending with parin’s

Question 20

what is the function of warfarin (anticoagulants)

Answer 20

inhibits vitamin K-dependent clotting factors synthesis ll, Vll, lX, and X made by the liver

Question 21

what is the function of antithrombin medications

Answer 21

inhibits thrombin (factor lla)

Question 22

what are the contraindications of anticoagulants

Answer 22

drug allergy, acute bleeding, warfarin not allowed in pregnancy

Question 23

ADR’s of anticoagulants

Answer 23

bleeding, heparin induced thrombocytopenia