Pharmacology Flashcards

1
Q

Ethambutol side effects

A

Optic neuritis, red-green colour blindness, peripheral neuropathy

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2
Q

Isoniazid side effects

A

Liver enzyme INHIBITOR agranulocytosis, hepatitis, peripheral neuropathy (prevent w B6)

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3
Q

Pyrazinamide side effects

A

Hyperuricaemia, hepatitis

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4
Q

Rifampicin side effects

A

Potent liver enzyme INDUCER, orange secretions, hepatitis

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5
Q

Amikacin side effects

A

amino glycoside side effects - nephrotoxic and ototoxic

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6
Q

Hyoscine

A

Dry mouth

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7
Q

Clozapine side effects

A

Excessive salivating

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8
Q

Amiodarone side effects

A

Altered taste

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9
Q

Worsened glycaemic control

A

Beta blockers, thiazides, glucocorticoids, anti-psychotics

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10
Q

thiazolidinedione (pioglitazone)

A

peripheral oedema (water retention)

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11
Q

PDE 5 inhibitor (sildenafil) contra-indications

A

Nitrates and nicorandil

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12
Q

SGLT2 inhibitors

A

Lower limb amputation

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13
Q

Bladder cancer

A

Pioglitazone, azo dyes

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14
Q

Metformin adverse effects

A

B12 deficiency, GI upset

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15
Q

Gingival hypertrophy causes

A

Nifedipine , amlodipine
Phenytoin
Ciclosporin

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16
Q

Alcohol dependence drugs

A

Disulfiram, Acamprosate

17
Q

Smoking cessation drug

A

Bupropion (wellbutrin)

18
Q

Lithium toxicity ECG

A

Reversible flattening of T waves, T wave inversion, isoelectricity

19
Q

Goserelin indications

A

Endometriosis
Breast, prostate CA
Precocious puberty
Uterine fibroids
Infertility

20
Q

Drug-induced dystonia treatment

A

Procyclidine 10mg IM