Pharmacokinetic Principles -1 (Routes Of Drug Administration) Flashcards
Any substance or product which used or, intended to be used, to modify or explore physiological systems or pathological states for the benefit of the recipient.
Drug.
Path by which a drug, fluid, poison, or other substance is taken into the body
Routes of drug administration
What are the two routes of drugs administration?
1- local.
2- systemic.
factors to be considered in routes of drug administration.
1- chemical properties of drugs.
2- onset of drug action.
3- convenience.
4- cost.
Site of action is the SAME as site of administration in which drug route?
Local route
Absorption of drug into systemic circulation is MINIMAL or ABSENT in which drug route?
Local routes.
Side effects are MINIMAL in which drug route?
Local routes.
What are the local routes?
1- topical.
2- deeper tissues.
3- arterial supply.
External application of the drug to surfaces for localized action?
Topical application.
On skin, nasal mucosa, oral mucosa, eyes, ear canals, anal canal, vagina, non-absorbable drugs given orally, inhalation of drugs for local action on bronchi.
1-On skin.
2-nasal mucosa.
3-oral mucosa.
4-eyes.
5-ear canals.
6-anal canal.
7-vagina.
8-non-absorbable drugs given orally.
9-inhalation of drugs for local action on bronchi.
Has to be reached with the help of a NEEDLE, is which drug route?
Deeper tissues.
Absorption of drug is minimal, is which drug route?
Deeper tissues.
Drugs act only LOCALLY at the site of administration, is which drug route?
Deeper tissues
Examples of deeper tissues drug routes?
1- intra articular injection.
2- intra thecal injection.
3-Intralesional injection.
4-intracardiac injection.
5-retrobulbar injection.
6- infiltration around a nerve.
Examples of arterial supply?
1-contrast media in angiography.
2-intra-arterial chemotherapy.
