Intro To Pharma Flashcards
The study of drug effects on various human systems
Pharmacology
The backbone of medicine
Pharmacology
A macromolecule in the membrane or inside the cell that chemically binds a ligand
Drug - receptor
All drugs must bind with a specific receptor except?
Antacid, mannitol
A chemical that binds to a receptor and activates it to produce a biological response, what is it and what does it have?
Agonist.
They have both efficacy and affinity.
Receptor ligand or drug that blocks or dampens a biological response. What is it and what does it have?
Antagonist.
They have affinity but no efficacy.
The science of drugs and their clinical use
Clinical pharmacology.
The science of poisons.
Toxicology.
The length of time it takes for a medicine to start to work.
Onset of action.
The length of time that particular drug is effective.
Duration of action.
Biological object under observation and the drug employed.
Dose response relationship.
An approximate assessment of the safety of the drug. The ratio of the median lethal dose and the median effective dose.
Therapeutic index, window or safety.
The time taken for drug plasma concentration to be reduced to half its original value.
Plasma half life.
Useful for determining excretion rates as well as steady state concentrations for any specific drug.
Plasma half life.
Plasma half life depends on?
1- Distribution half life.
2- Excretion half life.
