Pharmaco Flashcards

1
Q

Neurotransmetteur

A

Substance chimique libérée par un élément pré-synaptique après stimulation, qui active les récepteurs post-synaptique

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2
Q

Classes de neurotransmetteurs

A

1) Amines biogènes: NA, DA, 5HT, Ach, Histamine
2) Acides aminés: GABA, glutamatem glycine
3) Peptide: neurotensine, CCK, TRH

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3
Q

5HT

A

Sérotonine

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4
Q

Halopéridol

A

1ere génération d’antipsychotique

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5
Q

Antipsychotique atypique point de vue sx

A
  • Traiter sx négatif
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6
Q

Antipsychotique atypique point de vue pharmaco

A
  • Antagoniste dopamininergique ET sérotoninergique
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7
Q

Effet benzo

A

1- Relaxation musculaire
2- Effet anxiolytique
3- Effet anticonvulsilant
4- Effet sur l’Ataxie
- Effet hypnotique
- Effet amnésique

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8
Q

Traitement de l’agitation

A

BZD

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9
Q

Indication BZD

A
  • Anxiolytique
  • Hypnotique
  • Anticonvulsivants
  • Sédatifs
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10
Q

Contre-indication BZD

A
  • Hypersensibilité
  • Glaucome angle fermé
  • Apnée du sommeil
  • Insuffisance respiratoire sévère
  • Myasthénie grave
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11
Q

Mécanisme d’action BZD

A
  • Forte affinité avec récepteur GABA = Inhibiteur du SNC
  • Favorise l’entrée de Cl dand la cellule, = réduit l’excitabilité du SNC
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12
Q

Anti-psychotique 1ere gen

A

Halopéridol

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13
Q

Incisif

A

Bloque récepteur D2 TRÈS fortement
+ sx cognitif, prolactine
+ effet extra pyra

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14
Q

Anti-psychotique 2e gen

A

Rispéridone

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15
Q

Effet sur la prolactine sur les antipsychichotique

A

Augmentation de la prolactine

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