Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharma; Restart > Pharma Halo-halo > Flashcards

Pharma Halo-halo Flashcards

1
Q

Teratogenic effect of misoprostol

A

bilateral congenital paralysis of the abducens and facial nerves in combination with various odontological, craniofacial, ophthalmological and orthopaedic conditions.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Cutis laxa

A

Penicillamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Phocomelia

A

Thalidomide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Aplasia cutis congenita

A

Metimazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Warfarin teratogenic effects

A

1st tri: chondrodysplasia
2nd tri: CNS malformation
3rd tri: bleeding diatheses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Remarks on misoprostol

A

PGE1 analog
Causes increased bicarbonate and mucus secretion in the stomach
Used for prevention of NSAID-induced gastritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Arrhythmogenesis of digoxin is increased by

A

Hypokalemia
Hypomagnesemia
Hypercalcemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Most common ECG change seen in digoxin toxicity

A

Premature ventricular contractions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Antidote for methanol

A

Ethanol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Antidote for benzodiazepines

A

Flumazenil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Antidote for beta blockers

A

Glucagon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Antidote for cyanide

A

Hydroxocobalamin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Antidote for heparin

A

Protamin sulfate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Antidote for warfarin

A

Vitamin K, FFP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Drugs with hematologic side effects

A 
ANEMIA
Rifampicin
Spectinomycin
TZD (e.g. pioglitazone)
APLASTIC ANEMIA
Chloramphenicol
Carbamazepine
Colchicine
Probenecid
Sulfinpyrazone
Allopurinol
HEMOLYTIC ANEMIA
Methyldopa
Sulfasalazine
Penicillamine
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Moa of chloramphenicol

A 
Inhibits transpeptidation (peptidyl transferase) at 50S subunit
Bacteriostatic (but is bactericidal to H influenzae, Neisseria, bacteroides, S pneumoniae
17
Q

Myeloid growth factor

A

Filgrastim
Sargramostim
Plerixafor

18
Q

Megakaryocyte growth factor

A

Oprelvekin (IL-11)
Eltrombopag (TPO receptor agonist)
Romiplastim

19
Q

Dimercaprol

A

Acute arsenic poisoning
Acute mercury poisoning
Chronic led poisoning

20
Q

Succimer

A

Lead poisoning

Oral treatment

21
Q

Used for copper poisoning

A

Penicillamine

22
Q

EDTA

A

For chronic lead poisoning (severe)

23
Q

S/e of valproic acid

A

GI upset (m/c)
Fine tremor (at high doses)
Hepatotoxicity
*highly protein bound (90%)

Pharma; Restart (11 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions