Pharma 3.3

Question 1

TCA, smokingcessation

Answer 1

Bupropion

Se: weightloss, priapisim, seizures

Question 2

MAOi A?

Answer 2

Phenelzine

Question 3

Remarks on fentanyl

Answer 3

For severe pain
Breakthrough cancer pain
Available in lollipop form or transdermal patch

Question 4

Remarks on nalbuohene

Answer 4

Balanced anesthesia

Frequently abused by heathcare professionals

Question 5

Remaks on na,trexone

Answer 5

Tx of opioid dependence

Question 6

Opiod with shortest half life

Answer 6

Remifentanil

3-4 mins

Question 7

Opioid with longest halflife

Answer 7

Buprenorphine

4-8hrs

Question 8

Treatment of acromegaly, variceal bleed

Answer 8

Octreotide

Question 9

Drugs that can causes drug-induced hyperthyroidism

Answer 9

Clofibrate
Amiodarone
Methadone

Question 10

OCP of choice in lactating women

Answer 10

DMPA

Question 11

Anabolic steroids, illegal performance enhancers

Answer 11

Oxandrolone

Question 12

Tx of prostate CA

Coadministeredto prevent acute flareups of tumor

Answer 12

Flutamide + leuprolide

Question 13

5a reductase inhibitor

Answer 13

Finasteride

Tx of BPH and male pattern baldness

Question 14

1st gen SU

SE: hypoglycemia, weight gain, disulfiram rxn

Answer 14

Chlorpropamide

Question 15

2nd gen SU

Answer 15

Glipizide

Question 16

Newer insulin secretagogue

No hypoglycemia

Answer 16

Repaglinide

Question 17

Remarks on TZD

Answer 17

Pioglitazone
Acts on PPAR-y
Insulin sensitizer
SE: CHF

Question 18

Inactive vit D

Tx of rickets and osteomalacia

Answer 18

Ergocalciferol

Question 19

Stimullant laxative

Answer 19

Senna

S/e: melanosis coli

Question 20

Rescue agent for cyclophosphamide

Answer 20

MESNA

Question 21

For lymphoma

S/e: marked vesicant actions (skin blistering)

Answer 21

Mechlorethamine

*MOPP

Question 22

Antineoplastic for colon cancer

Answer 22

Cisplatin, carboplatin
S/e: ototoxicity, nephrotoxicity
Rescue agent: amifostine

Question 23

For lymphoma

S/e disulfiram reaction

Answer 23

Procarbazine

S/e: leukemogenesis

Question 24

For testicular cancer, antineoplastic

Answer 24

BLEOMYCIN

• most specific for G2 phase
• s/e: pulmonary fibrosis
• bone marrow-sparing

Question 25

Antineoplastic for brain tumor

Answer 25

Carmustine

Question 26

Causes thymine-less death of cells

Answer 26

5-FLUOROURACIL

• treatment of colorectal and skin cancer
• s/e: myelosuppression

Question 27

Inhibits ribonucleotide reductase

Answer 27

Gemcitabine

-treatment of pancreatic cancer

Question 28

Remarks on etoposide

Answer 28

Podophyllotoxin
Inhibits topoisomerase II
Tx of lung Ca, non-hodgkin’s lympoma, GTN

Question 29

Remarks on topotecan

Answer 29

Camptothecin
Inhibits DNA topoisomerase I
Treatment of small cell lung cancer

Question 30

Remarks on paclitaxel

Answer 30

Prevents microtubule disassembly

For advanced breast and ovarian cancers

Question 31

Remarks on doxorubicin

Answer 31

Intercalating agent
S/e: dilate cardiomyopathy
Rescue agent: dexrazoxane

Question 32

Treatment of melanoma

Answer 32

Actinomycin D

Also for wilms tumor and GTN

Question 33

Drugs that cause pulmonary fibrosis

Answer 33

Bleomycin
Busulfan
Bromocriptin
Amiodarone
Nitrofurantoin
Methotrexate

Question 34

MOPP

Answer 34

Meclorethamine
Oncovin (vincristine)
Procarbazine
Prednisone

For lymphoma
S/e: marked vesicant actions (skin blistering)

Question 35

R CHOP

Answer 35

Rituximab
Cyclophosphamide
Hydroxydaunorubicin HCl (Doxorubicin)
Oncovin (vincristine)
Prednisone

Question 36

MOPP

Answer 36

Meclorethamine
Oncovin (vincristine)
Procarbazine
Prednisone

For lymphoma
S/e: marked vesicant actions (skin blistering)

Question 37

R CHOP

Answer 37

Rituximab
Cyclophosphamide
Hydroxydaunorubicin HCl (Doxorubicin)
Oncovin (vincristine)
Prednisone

for non-hodkin’s lymphoma