Pharma Effects on Specific Systems Flashcards

1
Q

General Anesthesia

A
  • Confusion + muscle weakness = most common
  • Can last for several days
  • Can result in retained pulmonary secretions = postural drainage + breathing techniques
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2
Q

Local Anesthesia

A
  • Diminished sensation + motor function

- Do NOT put heating modalities on/near transdermal patch -> accelerates absorption = toxic effects

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3
Q

Opioid Analgesic Agents

A
  • Sedation + respiratory depression
  • Schedule PT to coincide with max effectiveness of drug to allow PT to be more aggressive + better participation from pt
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4
Q

Nonsteroidal Anti-Inflammatory Agents

A
  • GI discomfort — UNLIKELY to have effect on PT session

- Not as strong as opioids but also don’t cause sedation

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5
Q

Antiarthritic Agents

A
  • Depends on type of agent
  • Glucocorticoid drugs = breakdown of tendon, bone or skin —— CAUTIOUS with aggressive stretching + strengthening exercises to decrease risk of FRACTURE and SOFT TISSUE INJURY
  • Some can cause joint pain + swelling
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6
Q

Antiepileptic Agents

A
  • Cerebellar side effects - ataxia, loss of coordination

- Skin conditions - dermatitis

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7
Q

Skeletal Muscle Relaxants

A
  • Sedation + muscle weakness
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8
Q

Anti-Parkinson’s Agents

A
  • Orthostatic hypotension

- Schedule PT to coincide with max effectiveness - 1 hour after administration with Levodopa

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9
Q

Antihypertensive Agents

A
  • Orthostatic hypotension
  • Avoid interventions that cause widespread VASODILATION - ex: whirlpool
  • Use RPE if they have diminished HR response to exercise (Beta blockers)
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10
Q

Antianginal Agents

A
  • Orthostatic hypotension
  • Avoid interventions that cause widespread VASODILATION - ex: whirlpool
  • Use RPE
  • Some pts may have increased exercise tolerance because they are not limited by angina
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11
Q

Antiarrhythmic Agents

A
  • Can cause increase in arrhythmias or change in type of arrhythmia
  • If using Beta blockers or calcium channel blockers = OH
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12
Q

CHF Agents

A
  • Depends on type of drug
  • Diuretics = fatigue + muscle weakness associated with diminished fluid + electrolyte levels
  • Vasodilating drugs = OH = avoid interventions that cause widespread vasodilation = whirlpool
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13
Q

Anticoagulant Agents

A
  • Increased risk of bleeding

- Interventions that can cause tissue trauma (soft tissue massage, chest percussion, etc) performed with CAUTION

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14
Q

Respiratory Agents

A
  • Bronchodilators - cardiac arrhythmias, confusion, + tremors = signs of toxicity = closely monitor
  • Mucolytic + expectorant agents - no significant side effects - NEED to be taken 30-60 min before chest PT for max effectiveness
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15
Q

Sedative-hypnotic + Antianxiety Agents

A
  • Drowsiness, increased risk of falls + injury

- AVOID scheduling PT a few hours after taking because pt is too drowsy to actively participate

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16
Q

Antidepressant Agents

A
  • Depends on type
  • Lithium + tricyclics = sedation + muscle weakness
  • Some cause and increased risk for OH while others cause increased risk for HTN
17
Q

Antipsychotic Agents

A
  • Extrapyramidal sx = dyskinesia + dystonia

- Monitor for changes in posture, balance, + movement pattern + NOTIFY personnel IMMEDIATELY

18
Q

GI Agents

A
  • Side effects do not interrupt PT

- Minor side effects = dizziness, fatigue, + GI disturbances

19
Q

Adrenocorticosteroid Agents

A
  • Glucocorticoid drugs = breakdown of tendon, bone or skin —— CAUTIOUS with aggressive stretching + strengthening exercises to decrease risk of FRACTURE and SOFT TISSUE INJURY
  • Most effect on older, inactive pts with poor nutrition habits
  • Glucocorticoid + mineralocorticoid drugs can lead to water retention + contribute to HTN - MONITOR BP
20
Q

Sex Hormone Replacement Therapy

A
  • Estrogen, progesterones, + androgens = salt + water retention = HTN - MONITOR BP
21
Q

Thyroid Agents

A
  • Side effects associated with sx of the opposite condition
  • Parathyroid - calcium supplementation -> cardiac arrhythmias if used in excessive amounts - PT monitor cardiac function to avoid drug toxicity
22
Q

Insulin Replacement Therapy

A
  • Hypoglycemia - (see notecard for sx)

- Monitor + provide source of glucose if needed

23
Q

Antibacterial Agents

A
  • Hypersensitivity of skin or respiratory tract

- CAUTION with use of UV light treatment

24
Q

Chemotherapy Agents

A
  • Severe fatigue - will be days when pt cannot tolerate even a light workload
  • Toxic effects of CNS + PNS - AWARE of peripheral neuropathy or ataxia
25
Q

Immunomodulating Agents

A
  • Catabolic effects on muscle, tendon + bone - CAUTIOUS with aggressive stretching + strengthening exercises to decrease risk of FRACTURE and SOFT TISSUE INJURY
  • Balance + gait impairments 2* peripheral neuropathy or CNS damage