Pharma Dr, Mariko lec 9 Flashcards
1
Q
voltage-gated Na+ channel
classification
function?
A
ion channels
generate and propagate action potential
2
Q
local anesthetics
mechanism?
application?
A
- block voltage-gated Na+ channels
- block action potential generation and propagation
reduce pain
3
Q
voltage-gated Na+ channel
properties?
A
selectively Na+ permeable
- opens when plasma membrane is depolarized.
- closes shortly
- stay inactivated for a while
4
Q
voltage-gated Na+ channel
localization?
A
peripheral nerves and central nerves
