Pharma Dr, Mariko lec 15 Flashcards
1
Q
Anti-parkinsonism drugs and anti-psychotic drugs target…
A
dopamine receptors
2
Q
dopamine receptors classification function localization
A
G protein-coupled receptor
motor control
nigrostriatal system
3
Q
dopamine receptors
properties
A
D1 -like receptors: excitatory
D2-like receptors: inhibitory
4
Q
Drugs that work on dopamine receptors
2
A
L-DOPA
Antiphychotics
5
Q
L-DOPA
function
mechanism
application
A
dopamine precursor
compensate the loss of dopamine
Parkinson disease
6
Q
Antipsychotics
function
mechanism
application
A
dopamine D2 receptor antagonists
block D2 receptors
schizophrenia