Pharma Dr, Mariko lec 15 Flashcards

1
Q

Anti-parkinsonism drugs and anti-psychotic drugs target…

A

dopamine receptors

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2
Q
dopamine receptors 
classification
function
localization
A

G protein-coupled receptor
motor control
nigrostriatal system

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3
Q

dopamine receptors

properties

A

D1 -like receptors: excitatory

D2-like receptors: inhibitory

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4
Q

Drugs that work on dopamine receptors

2

A

L-DOPA

Antiphychotics

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5
Q

L-DOPA
function
mechanism
application

A

dopamine precursor

compensate the loss of dopamine
Parkinson disease

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6
Q

Antipsychotics
function
mechanism
application

A

dopamine D2 receptor antagonists

block D2 receptors
schizophrenia

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