Pharma Dr, Mariko lec 10 Flashcards

1
Q

nicotinic acetylcholine receptor

function?

A

channel opening allows Na influx leading to membrane depolarization and action potential initiation.

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2
Q

nicotinic acetylcholine receptor

localization? 3 sites

A
neuromuscular junctions (NMJ)
autonomic ganglia
central nervous system
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3
Q

Drug targeting the nicotine acetylcholine recepto

A

neuromuscular-blocking agents

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4
Q

Neuromuscular-blocking agents

mechanism

A

antagonists block transmission as blockers

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5
Q

Neuromuscular-blocking agents

Application

A

neuromuscular blocking agents are used to produce muscle relaxation in anesthetized patients during surgery

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6
Q

ganglionic blocking agents and neuro-muscular agents target…

A

nicotinic acetylcholine receptors

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