Pharma Dr, Mariko lec 13, Flashcards
Sympathomimetic drugs and sympatholytic drugs target
adrenergic receptors
Adrenergic receptors
classification
properties
G protein coupled receptor
Both noradrenaline and adrenaline activate adrenergic receptors
Adrenergic receptor
3 types of receptors and their functions
alpha1- contracts smooth muscle
beta1- increases in the rate and force of the heart
beta2- adrenergic receptor relaxes smooth muscle
Adrenergic receptors localization
target organs of post-ganglionic sympathetic fibers
drugs works on the adrenergic receptors
3 types
alpha1 receptor antagonists
beta2 receptor agonist
beta1 receptor antagonist
alpha 1 receptor antagonists
purpose and application
reduce blood pressure
antihypertensive
beta2 receptor agonist
purpose and application
bronchodilation
asthma treatment